Now showing items 1-10 of 1068
Molecular modeling of the α9α10 nicotinic acetylcholine receptor subtype
This study reports the comparative molecular modeling, docking and dynamic simulations of human α9α10 nicotinic acetylcholine receptors complexed with acetylcholine, nicotine and α-conotoxin RgIA, using as templates the ...
Functional expression of the α7 and α4-containing nicotinic acetylcholine receptors on the neonatal rat carotid body
The carotid bodies (CBs) are chemosensory organs that respond to hypoxemia with transmitter neurosecretion, leading to a respiratory reflex response. It has been proposed that acetylcholine is a key regulator of transmitter ...
Acetylcholine contributes to control the physiological inflammatory response during the peri-implantation period
(Wiley Blackwell Publishing, Inc, 2015-06)
Maternal antigen-presenting cells attracted to the pregnant uterus interact with trophoblast cells and modulate their functional profile to favour immunosuppressant responses. Non-neuronal cholinergic system is expressed ...
Molecular modeling of the a9a10 nicotinic acetylcholine receptor subtype
(Elsevier Ltd., 2008-10-25)
This study reports the comparative molecular modeling, docking and dynamic simulations of human a9a10 nicotinic acetylcholine receptors complexed with acetylcholine, nicotine and a-conotoxin RgIA, using as templates the ...
Supplementing female rats with DHA-lysophosphatidylcholine increases docosahexaenoic acid and acetylcholine contents in the brain and improves the memory and learning capabilities of the pups
DHA has been established. We propose that DHAcontaining lysophosphatidylcholine (DHA-LPC), obtained from DHA-rich eggs may be a suitable form of DHA and choline (the precursor of acetylcholine) supplementation. We ...
Electrogravimetric Analysis by Quartz-Crystal Microbalance on the Consumption of the Neurotransmitter Acetylcholine by Acetylcholinesterase
Electrogravimetric analysis was performed on the consumption of the neurotransmitter Acetylcholine (ACh) by Acetylcholinesterase (AChE) in situ and in real time. Michaelis-Menten assumption was achieved by using an enzyme ...
The alpha 7, alpha 4 beta 2 and alpha 3 beta 4 Nicotinic Acetylcholine Receptors: Characteristics, Role in Pathogenic Processes and Bioactive Compounds
(Brazilian Chemical Soc, 2016-01-01)
Neuronal nicotinic acetylcholine receptors (nAChRs) are potential targets for the treatement of several central nervous system disorders, including Alzheimer's disease, Parkinson's disease and schzophrenia. On this review ...
Role of acetylcholine receptors in proliferation and differentiation of P19 embryonal carcinoma cells
(ELSEVIER INC, 2008)
Coordinated proliferation and differentiation of progenitor cells is the base for production of appropriate numbers of neurons and glia during neuronal development in order to establish normal brain functions. We have used ...
Conformational and stereoeletronic investigations of muscarinic agonists of acetylcholine by NMR and theoretical calculations
(Elsevier Science BvAmsterdamHolanda, 2012)