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Comparison of effects of clodronate and zoledronic acid on the repair of maxilla surgical wounds - histomorphometric, receptor activator of nuclear factor-kB ligand, osteoprotegerin, von Willebrand factor, and caspase-3 evaluation
(John Wiley & Sons A/SPorto Alegre, 2012)
BACKGROUND: The aim of this study was to compare clodronate and zoledronic acid regarding their influence on the repair of surgical wounds in maxillae (soft tissue wound and tooth extraction) and their relation to ...
Comparison of effects of clodronate and zoledronic acid on the repair of maxilla surgical wounds - histomorphometric, receptor activator of nuclear factor-kB ligand, osteoprotegerin, von Willebrand factor, and caspase-3 evaluation
(John Wiley & Sons A/SPorto Alegre, 2012)
BACKGROUND: The aim of this study was to compare clodronate and zoledronic acid regarding their influence on the repair of surgical wounds in maxillae (soft tissue wound and tooth extraction) and their relation to ...
Zoledronic acid and alendronate sodium and the implications in orthodontic movement
(Wiley-Blackwell, 2017-08-01)
Structured Abstract ObjectiveTo evaluate orthodontic tooth movement (OTM) in rats treated with two types of bisphosphonates (BPs), alendronate sodium (A) and zoledronic acid (Z). DesignIn all, 15 male Wistar rats were ...
Zoledronate and related impurities analysis by capillary zone electrophoresis
(Bentham Science Publishers, 2014-06)
A capillary zone electrophoretic (CZE) method has been developed for the determination of zoledronate and its related impurities (phosphyte and phosphate). Successful separation of the drug from the impurities was achieved ...
Association between bisphosphonates and jaw osteonecrosis: a study in Wistar rats
(Wiley Periodicals, IncPorto Alegre, 2011)
BACKGROUND: This work aimed at determining whether bisphosphonate therapy produces a sufficient condition for jaw osteonecrosis after tooth extraction. METHODS: Rats were allocated into 3 groups: (1) 11 rats treated with ...
Association between bisphosphonates and jaw osteonecrosis: a study in Wistar rats
(Wiley Periodicals, IncPorto Alegre, 2011)
BACKGROUND: This work aimed at determining whether bisphosphonate therapy produces a sufficient condition for jaw osteonecrosis after tooth extraction. METHODS: Rats were allocated into 3 groups: (1) 11 rats treated with ...
Long-term therapy with intravenous zoledronate increases the number of nonattached osteoclasts
(2017-11-01)
The purpose of this study was to investigate the influence of long-term therapy with intravenous zoledronate (ZA) on the healing of extraction sockets in rats. Forty rats, divided into groups C (Control) and Z (Zoledronate), ...
Sequential treatment with monofluorophosphate and zoledronic acid in osteoporotic rats
(Taylor & Francis Ltd, 2014-08)
Objective Osteoporosis is the consequence of an imbalance in bone remodeling caused by excessive resorption or inappropriate bone formation. This paper proposes a sequential treatment with monofl uorophosphate (MFP) and ...
OPG-Fc but Not Zoledronic Acid Discontinuation Reverses Osteonecrosis of the Jaws (ONJ) in Mice
(Wiley-Blackwell, 2015-09-01)
Osteonecrosis of the jaws (ONJ) is a significant complication of antiresorptive medications, such as bisphosphonates and denosumab. Antiresorptive discontinuation to promote healing of ONJ lesions remains highly controversial ...
Influence of bisphosphonates on oral implantology: Sodium alendronate and zoledronic acid enhance the synthesis and activity of matrix metalloproteinases by gingival fibroblasts seeded on titanium
(2021-07-01)
Objective: This study aimed to assess the influence of the bisphosphonates zoledronic acid and sodium alendronate on MMP-2 and MMP-9 synthesis and activity by gingival fibroblasts seeded onto titanium substrate. Design: ...