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A Proline-Rich N-Terminal Region of the Dengue Virus NS3 Is Crucial for Infectious Particle Production
(American Society for Microbiology, 2016-05)
Dengue virus is currently the most important insect-borne viral human pathogen. Viral nonstructural protein 3 (NS3) is a key component of the viral replication machinery that performs multiple functions during viral ...
Dengue virus capsid protein usurps lipid droplets for viral particle formation
(BioMed Central, 2019)
Dengue virus capsid protein usurps lipid droplets for viral particle formation
(BioMed Central, 2009)
Dengue virus capsid protein usurps lipid droplets for viral particle formation
(Public Library of Science, 2009-10)
Dengue virus is responsible for the highest rates of disease and mortality among the members of the Flavivirus genus. Dengue epidemics are still occurring around the world, indicating an urgent need of prophylactic vaccines ...
Uncoupling cis-Acting RNA elements from coding sequences revealed a requirement of the N-terminal region of dengue virus capsid protein in virus particle formation
(American Society For Microbiology, 2012-01)
Little is known about the mechanism of flavivirus genome encapsidation. Here, functional elements of the dengue virus (DENV) capsid (C) protein were investigated. Study of the N-terminal region of DENV C has been limited ...
Hantavirus Gn and Gc Glycoproteins Self-Assemble into Virus-Like Particles
(2014)
How hantaviruses assemble and exit infected cells remains largely unknown. Here, we show that the expression of Andes (ANDV) and Puumala (PUUV) hantavirus Gn and Gc envelope glycoproteins lead to their self-assembly into ...
Detecção do Foot-and-mouth disease virus em líquido esofágico faríngeo (LEF) bovino por RT-qPCR análise comparativa do desempenho de reagentes de inativação viral
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE MICROBIOLOGIAPrograma de Pós-Graduação em MicrobiologiaUFMG, 2020-10-19)
FMD is caused by foot-and-mouth disease virus (FMDV), an RNA virus of the family Picornaviridae, which infects biungulate animals, ruminants and domestic and wild swine throughout the world. Seven viral serotypes are ...
Neutrophil extracellular traps possess anti-human respiratory syncytial virus activity: Possible interaction with the viral F protein
(2018-06-02)
Human respiratory syncytial virus (hRSV) is one of the main etiological agents of diseases of the lower respiratory tract, and is often responsible for the hospitalization of children and the elderly. To date, treatments ...
Characterization of rotavirus guanylyltransferase activity associated with polypeptide VP3
(1991)
Rotaviruses transcribe mRNA containing a 7(m)GpppG(m)p cap at the 5' end in vitro. Guanylyltransferase activity associated with the viral particle was detected by SDS-PAGE due to the formation of a nucleotide-enzyme complex ...
Physical factors affecting plasmid DNA compaction in stearylamine-containing nanoemulsions intended for gene delivery
(2012-06-13)
Cationic lipids have been used in the development of non-viral gene delivery systems as lipoplexes. Stearylamine, a cationic lipid that presents a primary amine group when in solution, is able to compact genetic material ...