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Ongoing HIV-1 evolution and reservoir reseeding in two elite controllers with genetically diverse peripheral proviral quasispecies
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz, 2023)
Modeling the Dynamics of Viral Evolution Considering Competition Within Individual Hosts and at Population Level: The Effects of Treatment
(SPRINGER, 2010)
We consider two viral strains competing against each other within individual hosts (at cellular level) and at population level (for infecting hosts) by studying two cases. In the first case, the strains do not mutate into ...
Plasma viral load threshold for sustaining intrahost HIV type 1 evolution
(Mary Ann Liebert, 2018)
Simulação computacional e análise de um modelo fenotípico de evolução viral
(Universidade Federal de São Paulo (UNIFESP), 2011-01-26)
A large amount of viruses of medical importance such as HIV, respiratory syncytial virus, the hepatitis C virus, influenza A (H1N1) and polio virus, has RNA genome. These viruses exhibit extremely high mutational rate, ...
Evidence of bottleneck effect on hepatitis C virus transmission between a couple under interferon based therapy
(2017-01-01)
Issues on the correlation of viral genetic diversity and treatment response to the hepatitis C infection remain uncertain. The bottleneck effect dictates the characteristics of the viral population that will establish the ...
A novel SARS-CoV-2 viral sequence bioinformatic pipeline has found genetic evidence that the viral 3 ' untranslated region (UTR) is evolving and generating increased viral diversity
(Frontiers Media, 2021)
An unprecedented amount of SARS-CoV-2 sequencing has been performed, however,
novel bioinformatic tools to cope with and process these large datasets is needed.
Here, we have devised a bioinformatic pipeline that inputs ...
Complete Genome Viral Phylogenies Suggests the Concerted Evolution of Regulatory Cores and Accessory Satellites
(PUBLIC LIBRARY SCIENCE, 2008)
We consider the concerted evolution of viral genomes in four families of DNA viruses. Given the high rate of horizontal gene transfer among viruses and their hosts, it is an open question as to how representative particular ...
The mystery of the phylogeographic structural pattern in rodent-borne hantaviruses
(Elsevier 12 Months, 2019)
Viral intra-host evolution in immunocompetent children contributes to human norovirus diversification at the global scale.
(Taylor and Francis, 2021)
Norovirus is a major cause of acute gastroenteritis. Human noroviruses present >30 different genotypes, with a single genotype (GII.4) predominating worldwide. Concurrent outbreaks of norovirus are often associated with ...
Viral diseases and human evolution
(Instituto Oswaldo Cruz, Ministério da Saúde, 2000-01-01)
The interaction of man with viral agents was possibly a key factor shaping human evolution, culture and civilization from its outset. Evidence of the effect of disease, since the early stages of human speciation, through ...