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Requirement for Ergosterol in V-ATPase Function Underlies Antifungal Activity of Azole Drugs
(Public Library of Science, 2010-06)
Ergosterol is an important constituent of fungal membranes. Azoles inhibit ergosterol biosynthesis, although the cellular basis for their antifungal activity is not understood. We used multiple approaches to demonstrate a ...
Short- and long-term, salinity-induced modulation of V-ATPase activity in the posterior gills of the true freshwater crab, Dilocarcinus pagei (Brachyura, Trichodactylidae)
(ELSEVIER SCIENCE INC, 2011)
To better understand the biochemical mechanisms underlying anisosmotic extracellular regulation in the freshwater Brachyura, we kinetically characterized the V-ATPase from the posterior gills of Dilocarcinus pagei, acclimated ...
Cimetidine-induced androgenic failure causes cell death and changes in actin, EGF and V-ATPase immunoexpression in rat submandibular glands
(2021-01-01)
Submandibular gland (SMG) is responsive to androgens via androgen receptor (AR). We verified whether cimetidine induces androgenic dysfunction in SMG, and evaluated the structural integrity, cell death and immunoexpression ...
Differential adjustment in gill Na(+)/K(+)- and V-ATPase activities and transporter mRNA expression during osmoregulatory acclimation in the cinnamon shrimp Macrobrachium amazonicum (Decapoda, Palaemonidae)
(COMPANY OF BIOLOGISTS LTD, 2010)
We evaluate osmotic and chloride (Cl(-)) regulatory capability in the diadromous shrimp Macrobrachium amazonicum, and the accompanying alterations in hemolymph osmolality and [Cl(-)], gill Na(+)/K(+)-ATPase activity, and ...
Cloning and characterization of a V-ATPase subunit C from the American visceral leishmaniasis vector Lutzomyia longipalpis modulated during development and blood ingestion
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)
Resistência a mosca branca (Bemisia tabaci) em plantas transgênicas expressando siRNA do gene de uma v-ATPase
(2016-04-05)
RNA de interferência (RNAi) é um processo bioquímico potente e específico de silenciamento de genes, que ocorre em uma variedade de organismos como mamíferos, fungos e plantas. O mecanismo atua a nível pós-transcricional, ...
Identificação de Drivers Moleculares no Tumor de Células Granulares Oral
(Universidade Federal de Minas GeraisBrasilMEDICINA - FACULDADE DE MEDICINAPrograma de Pós-Graduação em Medicina MolecularUFMG, 2020-07-09)
Granular cell tumor (GCT) is a benign soft tissue neoplasm of unknown pathogenesis that mainly affects the head and neck region. GCTs are derived from Schwann cells and, utrastructurally, their intracytoplasmic granules ...
Spermathecae: Morphofunctional features and correlation with fat bodies and trachea in six species of vectors of Chagas disease
(2019-09-01)
Since spermatheca is able to transport spermatozoa and maintain a specific microenvironment for the storage of viable sperm cells for long periods of time, specific morphofunctional features must be involved in this capacity, ...
In vitro characterization of acid secretion in the gilthead sea bream (Sparus aurata) stomach
(ELSEVIER SCIENCE INC, 2014)
Cloning and characterization of a V-ATPase subunit C from the American visceral leishmaniasis vector Lutzomyia longipalpis modulated during development and blood ingestion
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2007)