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Confronting the barriers to develop novel vaccines against brucellosis
(Expert Reviews, 2011-09)
Brucellosis is an important zoonotic disease of nearly worldwide distribution. This pathogen causes abortion in domestic animals and undulant fever, arthritis, endocarditis and meningitis in humans. Currently, there is no ...
Rare detection of bordetella pertussis pertactin-deficient strains in Argentina
(Centers Disease Control, 2019-11)
Pertussis resurgence had been attributed to waning vaccine immunity and Bordetella pertussis adaptation to escape vaccine-induced immunity. Circulating bacteria differ genotypically from strains used in production of ...
Challenges in foot-and-mouth disease virus strain selection as an input to attain broad vaccine intraserotype cross-protection
(Taylor & Francis, 2021-02)
Introduction: Vaccination against foot-and-mouth disease virus is regarded as the most effective way to prevent disease. Selection of appropriate vaccine strains is challenging due to lack of cross-protection between ...
New Pertussis Vaccines: A Need and a Challenge
(Springer Verlag Berlín, 2019-11)
Effective diphtheria, tetanus toxoids, whole-cell pertussis (wP) vaccines were used for massive immunization in the 1950s. The broad use of these vaccines significantly reduced the morbidity and mortality associated with ...
Is The Time Coming for Plant-Made Vaccines?
(SciTechnol, 2012-10)
An editorial about the state-of-the-art of R&D for vaccines produced in plant platforms and the future expectations.
A novel MHC-II targeted BVDV subunit vaccine induces a neutralizing immunological response in guinea pigs and cattle
(Wiley Blackwell Publishing, Inc, 2020-12)
Bovine viral diarrhoea virus (BVDV) is a major cause of economic loss in the cattle industry, worldwide. Infection results in reduced productive performance, growth retardation, reduced milk production and increased ...
Advances in novel vaccines for foot and mouth disease: focus on recombinant empty capsids
(Taylor & Francis, 2019-01)
Foot and mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, which causes severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV). ...
Protection induced by a glycoprotein E-deleted bovine herpesvirus type 1 marker strain used either as an inactivated or live attenuated vaccine in cattle
(BMC, 2014-01)
Background: Bovine herpesvirus type 1 (BoHV-1) is the causative agent of respiratory and genital tract infections; causing a high economic loss in all continents. Use of marker vaccines in IBR eradication programs is widely ...
Covid-19 vaccination certificates and lifting public health and social measures: ethical considerations
(World Health Organization Regional Office for the Eastern Mediterranean, 2022-03)
As countries roll out their COVID-19 vaccination programs, a policy question to consider is whether, and under what conditions, it would be acceptable to lift or ease non-pharmaceutical public health measures such as social ...
Cost-utility analysis of dengue vaccination in a country with heterogeneous risk of dengue transmission
(Elsevier, 2016-01)
BACKGROUND:Dengue is one of the most important vector-borne diseases worldwide, and annually, nearly 390 million people are infected and 500,000 patients are hospitalized for severe dengue. Argentina has great variability ...