Now showing items 1-10 of 153
Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis
Hypoxia, a common condition of the tumor microenvironment, is associated with poor patient prognosis, tumor cell migration, invasion and metastasis. Recent evidence suggests that hypoxia alters endosome dynamics in tumor ...
Hypoxia, hypoxia-inducible factor-1 alpha and vascular endothelial growth factor in a murine model of Schistosoma mansoni infection
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2010)
Functional alterations in macrophages after hypoxia selection
(Soc Experimental Biology MedicineMaywoodEUA, 2007)
Role of glycosylation in hypoxia-driven cell migration and invasion
(NLM (Medline), 2019)
Hypoxia, a common condition of the tumor microenvironment, induces changes in the proteome of cancer cells, mainly via HIF-1, a transcription factor conformed by a constitutively expressed β-subunit and an oxygen-regulated ...
The role of tumor hypoxia in MUC1-positive breast carcinomas
Mucin 1 (MUC1) is a glycoprotein that is expressed on apical cell membranes in a variety of normal tissues. MUC1 is involved in cell signaling, inhibition of cell-cell and cell matrix adhesion, apoptosis, proliferation, ...
Regulation of galectins by hypoxia and their relevance in angiogenesis: strategies and methods
Formation of an aberrant and heterogeneous vascular network is a key pathological event in the multistep process of tumor growth and metastasis. Pro-angiogenic factors are synthesized and released from tumor, stromal, ...
Prognostic value of vascular endothelial growth factor and hypoxia-inducible factor 1α in canine malignant mammary tumors
Mammary tumors are the most common type of tumor in dogs, with approximately half of these tumors being malignant. Hypoxia, characterized by oxygen levels below normal, is a known adverse factor to cancer treatment. The ...
Infection by Leishmania amazonensis in mice: A potential model for chronic hypoxia
(Elsevier Gmbh, Urban & Fischer VerlagJenaAlemanha, 2012)