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The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009)
The human embryonic-lethal abnormal vision (ELAV)-like protein. HuR, has been recently found to be involved in the regulation of protein synthesis. In this study we show that HuR participates in the translational control ...
Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells
(Portland Press Ltd, 2013-04-15)
The protein known as eIF5A (eukaryotic initiation factor 5A) has an elusive role in translation. It has a unique and essential hypusine modification at a conserved lysine residue in most eukaryotes. in addition, this protein ...
TISs-ST: a web server to evaluate polymorphic translation initiation sites and their reflections on the secretory targets
(Biomed Central LtdLondonInglaterra, 2007)
Conformational Response of 30S-bound IF3 to A-Site Binders Streptomycin and Kanamycin
(MDPI, 2016)
Aminoglycoside antibiotics are widely used to treat infectious diseases. Among them, streptomycin and kanamycin (and derivatives) are of importance to battle multidrug-resistant (MDR) Mycobacterium tuberculosis. Both drugs ...
Mapping eIF5A binding sites for Dys1 and Lia1: In vivo evidence for regulation of eIF5A hypusination
(2003-12-18)
The evolutionarily conserved factor eIF5A is the only protein known to undergo hypusination, a unique posttranslational modification triggered by deoxyhypusine synthase (Dys1). Although eIF5A is essential for cell viability, ...
Mapping eIF5A binding sites for Dys1 and Lia1: In vivo evidence for regulation of eIF5A hypusination
(2003-12-18)
The evolutionarily conserved factor eIF5A is the only protein known to undergo hypusination, a unique posttranslational modification triggered by deoxyhypusine synthase (Dys1). Although eIF5A is essential for cell viability, ...
Functional and Structural Analysis of the Internal Ribosome Entry Site Present in the mRNA of Natural Variants of the HIV-1
(PUBLIC LIBRARY SCIENCE, 2012)
The 5'untranslated regions (UTR) of the full length mRNA of the HIV-1 proviral clones pNL4.3 and pLAI, harbor an internal ribosomal entry site (IRES). In this study we extend this finding by demonstrating that the mRNA ...