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SMAD3 is essential for transforming growth factor-β1-induced urokinase type plasminogen activator expression and migration in transformed keratinocytes
(2012)
Transforming growth factor-β1 (TGF-β1) stimulates the extracellular matrix degrading proteases expression and cell migration in order to enhance cancer cells malignancy. In the present study, we analysed the role of ...
The Internal Region Leucine-rich Repeat 6 of Decorin Interacts with Low Density Lipoprotein Receptor-related Protein-1, Modulates Transforming Growth Factor (TGF)-beta-dependent Signaling, and Inhibits TGF-beta-dependent Fibrotic Response in Skeletal Muscles
(American Society for Biochemistry and Molecular Biology, 2012)
Decorin is a small proteoglycan, composed of 12 leucine-rich repeats (LRRs) that modulates the activity of transforming growth factor type β (TGF-β) and other growth factors, and thereby influences proliferation and ...
The Internal Region Leucine-rich Repeat 6 of Decorin Interacts with Low Density Lipoprotein Receptor-related Protein-1, Modulates Transforming Growth Factor (TGF)-beta-dependent Signaling, and Inhibits TGF-beta-dependent Fibrotic Response in Skeletal Muscles
(American Society for Biochemistry and Molecular Biology, 2012)
Decorin is a small proteoglycan, composed of 12 leucine-rich repeats (LRRs) that modulates the activity of transforming growth factor type β (TGF-β) and other growth factors, and thereby influences proliferation and ...
Caveolin-1 interacts and cooperates with the transforming growth factor-β type I receptor ALK1 in endothelial caveolae
(2008)
Aims: Activin receptor-like kinase (ALK)1 is a transforming growth factor (TGF)-β type I membrane receptor restricted almost entirely to endothelial cells (ECs) and involved in vascular remodelling and angiogenesis. Previous ...
Effect of transforming growth factor beta (TGF-β) receptor I kinase inhibitor on prostate cancer bone growth
(Elsevier Science Inc, 2012-03)
Transforming growth factor beta 1 (TGF-β1) has been implicated in the pathogenesis of prostate cancer (PCa) bone metastasis. In this study, we tested the antitumor efficacy of a selective TGF-β receptor I kinase inhibitor, ...
Matrix metalloproteinase-8 regulates transforming growth factor-β1 levels in mouse tongue wounds and fibroblasts in vitro
(Academic Press Inc., 2014)
© 2014 Elsevier Inc. Matrix metalloproteinase-8 (MMP-8)-deficient mice (Mmp8-/-) exhibit delayed dermal wound healing, but also partly contradicting results have been reported. Using the Mmp8-/- mice we investigated the ...
Active and Total Transforming Growth Factor-{beta}1 are Differentially Regulated by Dopamine and Estradiol in the Pituitary
(Endocrine Society, 2011-07)
Dopamine, acting through the dopamine type 2 receptor (Drd2), is the main inhibitor of pituitary prolactin (PRL) secretion and lactotroph proliferation. TGF-β1 is involved, at least in part, in mediating these actions. It ...
Association of increased levels of TGF-β1 and p14ARF in prostate carcinoma cell lines overexpressing Egr-1
(Spandidos Publications, 2014)
The present study examined the effect of the overexpression of early growth response gene (Egr-1) on transforming growth factor β-1 (TGF-β1) and p14ARFlevels, in PC-3 and LNCaP prostate carcinoma cell lines. Amplification ...