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Transcriptional and post-transcriptional control of the plant circadian gene regulatory network
(Elsevier Science, 2016-07-10)
The circadian clock drives rhythms in multiple physiological processes allowing plants to anticipate and adjust to periodic changes in environmental conditions. These physiological rhythms are associated with robust ...
Transcription initiation mapping in 31 bovine tissues reveals complex promoter activity, pervasive transcription, and tissue-specific promoter usage
(Cold Spring Harbor Laboratory Press, 2021-04)
Characterizing transcription start sites is essential for understanding the regulatory mechanisms that control gene expression. Recently, a new bovine genome assembly (ARS-UCD1.2) with high continuity, accuracy, and ...
ChIP-seq analysis of the LuxR-type regulator VjbR reveals novel insights into the Brucella virulence gene expression network
(Oxford University Press, 2017-03)
LuxR-type transcription factors control diverse physiological functions necessary for bacterial adaptation to environmental changes. In the intracellular pathogen Brucella, the LuxR homolog VjbR has been shown to regulate ...
Molecular mechanisms involved in functional macroevolution of plant transcription factors
(Wiley Blackwell Publishing, Inc, 2020-12)
Transcription factors (TFs) are key components of the transcriptional regulation machinery. In plants, they accompanied the evolution from unicellular aquatic algae to complex flowering plants that dominate the land ...
Class I TCP transcription factors regulate trichome branching and cuticle development in Arabidopsis
(Oxford University Press, 2020-09)
Trichomes and the cuticle are two specialized structures of the aerial epidermis that are important for plant organ development and interaction with the environment. In this study, we report that Arabidopsis thaliana plants ...
Local changes in chromatin accessibility and transcriptional networks underlying the nitrate response in Arabidopsis roots
(Oxford University Press, 2019-09)
Transcriptional regulation, determined by chromatin structure and regulatory elements interacting at promoter regions, is a key step in plant responses to environmental cues. Nitrate (NO3-) is a nutrient signal that regulates ...
A Predictive Coexpression Network Identifies Novel Genes Controlling the Seed-to-Seedling Phase Transition in Arabidopsis thaliana
(American Society of Plant Biologist, 2016-04)
The transition from a quiescent dry seed to an actively growing photoautotrophic seedling is a complex and crucial trait for plant propagation. This study provides a detailed description of global gene expression in seven ...
The BBX family of plant transcription factors
(Elsevier Science London, 2014-08)
The B-box (BBX) proteins are a class of zinc-finger transcription factors containing a B-box domain with one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. BBX proteins are key ...
A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases
(American Association for the Advancement of Science, 2015)
Early regulators of disease may increase understanding of disease mechanisms and serve as markers for presymptomatic diagnosis and treatment. However, early regulators are difficult to identify because patients generally ...
A predictive coexpression network identifies novel genes controlling the seed-to-seedling phase transition in arabidopsis Thaliana
(American Society of Plant Biologist, 2016-04)
The transition from a quiescent dry seed to an actively growing photoautotrophic seedling is a complex and crucial trait for plant propagation. This study provides a detailed description of global gene expression in seven ...