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A natural combinatorial chemistry strategy in acylpolyamine toxins from Nephilinae orb-web spiders
(Taylor & Francis Inc, 2005-01-01)
The present study shows how nature combined a small number of chemical building blocks to synthesize the acylpolyamine toxins in the venoms of Nephilinae orb-web spiders. Considering these structures in four parts, it was ...
Differential effects of novel wasp toxin on rat hippocampal interneurons
(Elsevier B.V., 2002-08-02)
We studied the effects of a wasp toxin beta-pompilidotoxin (beta-PMTX) on rat hippocampal CA1 interneurons by the current-clamp technique. The firing patterns of pyramidal neurons and pyramidale interneurons were not ...
Naturally acquired antibodies against Clostridium perfringens epsilon toxin in goats
(Elsevier B.V., 2008-09-15)
Clostridium perfringens type D-producing epsilon toxin is a common cause of death in sheep and goats worldwide. Although anti-epsilon toxin serum antibodies have been detected in healthy non-vaccinated sheep, the information ...
Laryngeal electromyography in movement disorders: Preliminary data
(2004-09-01)
This study describes preliminary laryngeal electromyography (LEMG) data and botulinum toxin treatment in patients with dysphonia due to movement disorders. Twenty-five patients who had been clinically selected for botulinum ...
Production and release of heat-labile toxin by wild-type human-derived enterotoxigenic Escherichia coli
(Blackwell Publishing, 2006-10-01)
Production and release of heat-labile toxin (LT) by wild-type enterotoxigenic Escherichia coli (ETEC) strains, isolated from diarrheic and asymptomatic Brazilian children, was studied under in vitro and in vivo conditions. ...
The chelation of metal ions by the acylpolyamine toxins from the web-spider Nephilengys cruentata: effects in the intoxication/detoxification of preys
(Birkhauser Verlag Ag, 2006-01-01)
Orb-web-spiders present a series of different strategies for prey capture, involving the use of different types of silk for web building, the use of adhesive traps in the webs, the secretion of toxic compounds to the ...
Survey of cytotoxin production among escherichia-coli strains characterized as enteropathogenic (epec) by serotyping and presence of epec adherence factor (eaf) sequences
(Natl Research Council Canada, 1994-05-01)
A total of 108 Escherichia coli strains characterized as enteropathogenic (EPEC) by serotyping and the presence of EPEC adherence factor (EAF) sequences were examined for cytotoxin production by cell line assays and colony ...
Nephrotoxicity caused by brown spider venom phospholipase-D (dermonecrotic toxin) depends on catalytic activity
(Elsevier B.V., 2008-11-01)
Bites from brown spiders (Loxosceles genus) have clinical manifestations including skin necrosis with gravitational spreading, and systemic involvement that may include renal failure, hemolysis, and thrombocytopenia. Mice ...
Purification of Candida guilliermondii and Pichia ohmeri killer toxin as an active agent against Penicillium expansum
(Taylor & Francis Ltd, 2009-01-01)
An antifungal assay with cell-free culture supernatant of Pichia ohmeri 158 and Candida guilliermondii P3 was tested against Penicillium expansum strain #2 at 25C by measuring hyphal length and percentage conidia germination. ...