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Trojan horse monocyte-mediated delivery of conjugated polymer nanoparticles for improved photodynamic therapy of glioblastoma
(Future Medicine, 2020-07)
Aim: To assess monocyte-based delivery of conjugated polymer nanoparticles (CPNs) for improved photodynamic therapy (PDT) in glioblastoma (GBM). Materials & methods: Human monocyte cells (THP-1) and murine monocytes isolated ...
Trojan-Like Internalization of Anatase Titanium Dioxide Nanoparticles by Human Osteoblast Cells
(Nature Publishing Group, 2016-03-29)
Dentistry and orthopedics are undergoing a revolution in order to provide more reliable, comfortable and long-lasting implants to patients. Titanium (Ti) and titanium alloys have been used in dental implants and total hip ...
NTS-Polyplex: a potential nanocarrier for neurotrophic therapy of Parkinson's disease
(2012)
Nanomedicine has focused on targeted neurotrophic gene delivery to the brain as a strategy to stop and reverse neurodegeneration in Parkinson's disease. Because of improved transfection ability, synthetic nanocarriers have ...
Antibacterial and antitumorigenic properties of microcin E492, a poreforming bacteriocin
(2009)
Microcins are a family of low-molecular weight bacteriocins produced and secreted by Gram-negative bacteria. This review is focused on microcin E492, a pore-forming bacteriocin produced by Klebsiella pneumoniae RYC492 that ...
A "Trojan horse" strategy to reverse drug-resistance in brain tumors
(Universidad del RosarioDoctorado en Ciencias BiomédicasFacultad de Ciencias Naturales y Matemáticas, 2014)
Malignant gliomas represent one of the most aggressive forms of Central Nervous System
(CNS) tumors. According to the WHO classification of brain tumors, astrocytomas have been
categorized into four grades, determined ...
NTS-Polyplex: A potential nanocarrier for neurotrophic therapy of Parkinson's disease
(2012)
Nanomedicine has focused on targeted neurotrophic gene delivery to the brain as a strategy to stop and reverse neurodegeneration in Parkinson's disease. Because of improved transfection ability, synthetic nanocarriers have ...
The association of statins plus LDL receptor-targeted liposome-encapsulated doxorubicin increases in vitro drug delivery across blood-brain barrier cells
Background and PurposeThe passage of drugs across the blood-brain barrier (BBB) limits the efficacy of chemotherapy in brain tumours. For instance, the anticancer drug doxorubicin, which is effective against glioblastoma ...
Fiber-particle morphological transition and its effect on impact strength of PS/HDPE blends
(2012)
Nanomedicine has focused on targeted neurotrophic gene delivery to the brain as a strategy to stop and reverse neurodegeneration in Parkinson's disease. Because of improved transfection ability, synthetic nanocarriers have ...