Now showing items 1-2 of 2
Assessing Tn5 and Sleeping Beauty for transpositional transgenesis by cytoplasmic injection into bovine and ovine zygotes
(Public Library of Science, 2017-03)
Transgenic domestic animals represent an alternative to bioreactors for large-scale production of biopharmaceuticals and could also provide more accurate biomedical models than rodents. However, their generation remains ...
Early fetal development of nuclear transfer bovine embryos generated from fibroblasts genetically modified by piggybac transposition
(Csiro Publishing, 2014-12-04)
Transposon-mediated transgenesis is a well-established tool for genome manipulation in small animal models. However, translation of this active transgenesis method to the large animal setting requires further investigation. ...