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Nuclear role for human Argonaute-1 as an estrogen-dependent transcription coactivator

Gómez Acuña, Luciana Inés; Nazer, Ezequiel; Rodríguez Seguí, Santiago Andrés; Pozzi, María Berta; Buggiano, Valeria Carmen; Marasco, Luciano Edmundo; Agirre, Eneritz; He, Cody; Alló, Mariano; Kornblihtt, Alberto Rodolfo (Rockefeller University Press, 2020-09)

In mammals, argonaute (AGO) proteins have been characterized for their roles in small RNA mediated posttranscriptional and also in transcriptional gene silencing. Here, we report a different role for AGO1 in estradiol-triggered ...

Short-term inhibition of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha expression reverses diet-induced diabetes mellitus and hepatic steatosis in mice

De Souza, CT; Araujo, EP; Prada, PO; Saad, MJA; Boschero, AC; Velloso, LA (SpringerNew YorkEUA, 2005)

Post-transcriptional control of GRF transcription factors by microRNA miR396 and GIF co-activator affects leaf size and longevity

Debernardi, Juan Manuel; Mecchia, Martin Alejandro; Vercruyssen, Liesbeth; Smaczniak, Cezary; Kaufmann, Kerstin; Inze, Dirk; Rodriguez Virasoro, Ramiro Esteban; Palatnik, Javier Fernando (Wiley, 2014-08)

The growth-regulating factors (GRFs) are plant-specific transcription factors. They form complexes with GRF-interacting factors (GIFs), a small family of transcriptional co-activators. In Arabidopsis thaliana, seven out ...

Solution structure of the C-terminal domain of multiprotein bridging factor 1 (MBF1) of Trichaderma reesei

SALINAS, Roberto K.; CAMILO, Cesar M.; TOMASELLI, Simona; VALENCIA, Estela Y.; FARAH, Chuck S.; EL-DORRY, Harnza; CHAMBERGO, Felipe S. (WILEY-LISS, 2009)

Progesterone upregulates GATA-1 on erythroid progenitors cells in liquid culture

Duarte, ADS; Sales, TSI; Mengel, JO; Costa, FF; Saad, STO (Academic Press Inc Elsevier ScienceSan DiegoEUA, 2002)

Steroid receptor coactivator-3 as a target for anaplastic thyroid cancer

Lee, W. K.; Kim, Won Gu; Fozzatti, Laura; Park, Sunmi; Zhao, Li; Willingham, Mark C.; Lonard, David; OMalley, Bert W.; Cheng, Sheue-yann (BioScientifica, 2020-01)

Anaplastic thyroid carcinoma (ATC) is an aggressive malignancy without effective therapeutic options to improve survival. Steroid receptor coactivator-3 (SRC-3) is a transcriptional coactivator whose amplification and/or ...

The catalytic subunit of schizosaccharomyces pombe CK2 (Cka1) negatively regulates RNA polymerase II transcription through phosphorylation of positive cofactor 4 (PC4)

Rojas, Diego A.; Urbina, Fabiola; Solari Illescas, Aldo Gerónimo; Maldonado Maldonado, Edio Luis (MDPI, 2022)

Positive cofactor 4 (PC4) is a transcriptional coactivator that plays important roles in transcription and DNA replication. In mammals, PC4 is phosphorylated by CK2, and this event downregulates its RNA polymerase II ...

Diverse coactivator recruitment through differential PPARγ nuclear receptor agonism

Autor desconocido (Genetics and Molecular Biology, 2013-03-04)

The PPARγ nuclear receptor regulates the expression of genes involved in lipid and carbohydrate metabolism, and it has protective effects in some patients with type 2 diabetes. Nevertheless, the therapeutic value of the ...

RAC‐3 is a NF‐κB coactivator

Werbajh, Santiago Enrique; Nojek Barbieri, Ignacio Martin; Lanz, Rainer; Costas, Monica Alejandra (Wiley, 2000-12)

It has been shown that the molecular mechanism by which cytokines and glucocorticoids mutually antagonize their functions involves a mutual glucocorticoid receptor (GR)/nuclear factor‐κB (NF‐κB) transrepression. Here we ...

Cold-induced PGC-1 alpha expression modulates muscle glucose uptake through an insulin receptor/Akt-independent, AMPK-dependent pathway

Oliveira, RLGS; Ueno, M; de Souza, CT; Pereira-da-Silva, M; Gasparetti, AL; Bezzera, RMN; Alberici, LC; Vercesi, AE; Saad, MJA; Velloso, LA (Amer Physiological SocBethesdaEUA, 2004)

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