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Increased production of soluble TLR2 by lamina propria mononuclear cells from ulcerative colitis patients
(2012)
Toll-like receptor 2 (TLR2) is a type I pattern recognition receptor that has been shown to participate in intestinal homeostasis. Its increased expression in the lamina propria has been associated with the pathogenesis ...
Toll-like receptor 4 gene polymorphism influences dendritic cell in vitro function and clinical outcomes in vaccinated melanoma patients
(2012)
Toll-like receptor 4 (TLR4) is expressed on dendritic cells (DCs), sensing environmental danger molecules that induce their activation and maturation. Recently, we reported a method for the production of therapeutic DCs ...
Dendritic Cells and Toll-Like Receptors 2 and 4 in the Ileum of Crohn's disease patients
(SPRINGER, 2008-07)
We investigated myeloid-dendritic cell (DC)
marker and Toll-like receptor (TLR)-2 and 4 distributions
in ileal samples from Crohn’s disease (CD) patients
(n = 14) and controls (n = 13). In controls, no TLR-2+
cells ...
Expression and function of toll-like receptor 4 and inflammasomes in cardiac fibroblasts and myofibroblasts: IL-1β synthesis, secretion, and degradation
(Elsevier Ltd, 2016)
© 2016 Elsevier Ltd. Cardiac inflammation can be produced by pathogen-associated molecular patterns (PAMPs), from parasitic, bacterial or viral origin; or by danger-associated molecular patterns (DAMPs), released from dead ...
Sertraline and citalopram actions on gut barrier function
(Springer, 2020)
Introduction Disruption of intestinal barrier is a key component to various diseases. Whether barrier dysfunction is the cause or effect in these situations is still unknown, although it is believed that translocation of ...
Expression and function of TLR4-induced B1R bradykinin receptor on cardiac fibroblasts
(Elsevier, 2018-07-15)
Cardiac fibroblasts (CF) are key cells for maintaining extracellular matrix (ECM) protein homeostasis in the heart, and for cardiac repair through CF-to-cardiac myofibroblast (CMF) differentiation. Additionally, CF play ...
Expression and function of TLR4-induced B1R bradykinin receptor on cardiac fibroblasts
(Elsevier, 2018)
Cardiac fibroblasts (CF) are key cells for maintaining extracellular matrix (ECM) protein homeostasis in the heart, and for cardiac repair through CF-to-cardiac myofibroblast (CMF) differentiation. Additionally, CF play ...
Expression and function of toll-like receptor 4 and inflammasomes in cardiac fibroblasts and myofibroblasts: IL-1 beta synthesis, secretion, and degradation
(Elsevier, 2016)
Cardiac inflammation can be produced by pathogen-associated molecular patterns (PAMPs), from parasitic, bacterial or viral origin; or by danger-associated molecular patterns (DAMPs), released from dead cells after cardiac ...
Short Report: Mannose-Binding Lectin and Toll-Like Receptor Polymorphisms and Chagas Disease in Chile
(2012)
Mannose-binding lectin (MBL) and Toll-like receptor (TLR) polymorphisms may influence susceptibility
and manifestation of Trypanosoma cruzi infection. In northern Chile, we examined 61 asymptomatic patients with
chronic ...
Surface Immunogenic Protein of Streptococcus Group B is an Agonist of Toll-Like Receptors 2 and 4 and a Potential Immune Adjuvant
(MDPI, 2020)
Vaccine-induced protection against pathogens, especially subunit-based vaccines, are related to antigen properties but mainly in their ability to stimulate the immune system by the use of an adjuvant. Modern vaccines are ...