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Differential uPA expression by TGF-β1 in gingival fibroblasts
(2006)
Transforming Growth Factor-β1 (TGF-β1) plays a key role in connective tissue remodeling and inflammation. Under pathological conditions, like periodontal disease, fibroblasts may display an altered response to this growth ...
TGF-β receptor type II costameric localization in cardiomyocytes and host cell TGF-β response is disrupted by Trypanosoma cruzi infection
(Cambridge University Press, 2016)
Endotoxin-induced endothelial fibrosis is dependent on expression of transforming growth factors β1 and β2
(American Society for Microbiology, 2014)
During endotoxemia-induced inflammatory disease, bacterial endotoxins circulate in the bloodstream and interact with endo thelial cells (ECs), inducing dysfunction of the ECs. We previously reported that endotoxins induce ...
Spred2 inhibits TGF-β1-induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition
(2010)
TGF-β1 is a potent inductor of malignance in cancer cells. TGF-β1 stimulates the expression of extracellular matrix degrading proteases, cell migration and it is also involved in the epithelial-mesenchymal transition (EMT). ...
Association of increased levels of TGF-β1 and p14ARF in prostate carcinoma cell lines overexpressing Egr-1
(Spandidos Publications, 2014)
The present study examined the effect of the overexpression of early growth response gene (Egr-1) on transforming growth factor β-1 (TGF-β1) and p14ARFlevels, in PC-3 and LNCaP prostate carcinoma cell lines. Amplification ...
Melatonin treatment combined with TGF-β silencing inhibits epithelialmesenchymal transition in CF41 canine mammary cancer cell line
(2020-01-01)
Background: Mammary cancer is the most prevalent type of cancer in female dogs. The main cause of mortality is the occurrence of metastasis. The metastatic process is complex and involves the EpithelialMesenchymal Transition ...
TGF-β and new bone formation
(2006-09-01)
The aim of this work is to present, by a literature review, the principal characteristics of TGF-beta, in the regulation and new bone formation. © 2007 Sociedad Chilena de Anatomía.
The TGF-β Pathway as an Emerging Target for Chagas Disease Therapy
(American Society for Clinical Pharmacology and Therapeutics, 2017)
COX-2 and TGF-β expression in proliferative disorders of canine prostate
(2010-05-01)
COX-2 and TGF-β expression was determined in order to correlate non-neoplastic lesions, preneoplastic lesions and carcinoma in the prostate of dogs. The results show that neoplastic and preneoplastic lesions express more ...