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Relationship of regulatory T cells to Plasmodium falciparum malaria symptomatology in a hypoendemic region
(BMC, 2014)
Background: Previous data have suggested that regulatory T cells (Tregs) balance protective immune responses with immune mediated pathology in malaria. This study aimed to determine to test the hypothesis that Treg proportions ...
The role of regulatory T lymphocytes in the induced immune response mediated by biological vaccines
(Elsevier GmbH, 2006)
Immunotherapy has become a novel therapeutic alternative for various kinds of tumours. Recently, we have finalized the first phase I clinical study in Chile for the treatment of advanced malignant melanoma, using dendritic ...
Foxp3 expression is associated with aggressiveness in differentiated thyroid carcinomas
(Hospital Clinicas, Univ Sao PauloSao PauloBrazil, 2012)
DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes
(2009-09-15)
Background: Our group previously demonstrated that a DNA plasmid encoding the mycobacterial 65-kDa heat shock protein (DNA-HSP65) displayed prophylactic and therapeutic effect in a mice model for tuberculosis. This protection ...
Role of dendritic cells in the induction of lymphocyte tolerance
(Frontiers Media, 2015)
The ability of dendritic cells (DCs) to trigger tolerance or immunity is dictated by the context in which an antigen is encountered. A large body of evidence indicates that antigen presentation by steady-state DCs induces ...
Imbalanced expression of functional surface molecules in regulatory and effector T cells in systemic lupus erythematosus
(Associação Brasileira de Divulgação Científica, 2014-08-01)
Regulatory T (TREG) cells play an important role in maintaining immune tolerance and avoiding autoimmunity. We analyzed the expression of membrane molecules in TREG and effector T cells in systemic lupus erythematosus ...
T lymphocytes and macrophages in the intestinal tissues of dogs infected with Leishmania infantumLinfócitos T e macrófagos nos tecidos intestinais de cães infectados com Leishmania infantum
(2017-01-01)
This study was about a semi-quantitative analysis of T lymphocytes (CD4+ and CD8+, FoxP3+ regulatory T cells), and macrophages in the gut wall of dogs naturally infected with Leishmania infantum. Thirteen dogs were divided ...