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The Crystal Complex of Phosphofructokinase-2 of Escherichia coli with Fructose-6-phosphate. Kinetic and structural analysis of the allosteric atp inhibition
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2011-02-18)
Substrate inhibition by ATP is a regulatory feature of the phosphofructokinases isoenzymes from Escherichia coli (Pfk-1 and Pfk-2). Under gluconeogenic conditions, the loss of this regulation in Pfk-2 causes substrate ...
Enzyme Inhibition
(Leanerstv.com, 2012)
Enzyme Inhibition
(Leanerstv.com, 2016)
Crystallographic Structure of Phosphofructokinase-2 from Escherichia coli in Complex with Two ATP Molecules. Implications for Substrate Inhibition
(ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2008)
Phosphofructokinase-1 and -2 (Pfk-1 and Pfk-2, respectively) from Escherichia coli belong to different homologous superfamilies. However, in spite of the lack of a common ancestor, they share the ability to catalyze the ...
Impact of impurity on kinetic estimates from transport and inhibition studies
(AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, 2008)
Although in vitro transport/inhibition studies are commonly performed on impure drug candidates to screen for pharmacokinetic properties in early development, quantitative guidelines concerning acceptable impurity levels ...
Investigating the substrate specificity and oligomerisation of the leader protease of foot and mouth disease virus using NMR
(Elsevier B.V., 2007-11-02)
The leader protease (Lb(pro)) of foot-and-mouth disease virus frees itself during translation from the viral polyprotein by cleavage between its own C terminus and the N terminus of the subsequent protein, VP4. Lb(pro) ...
Crystallographic structure of phosphofructokinase-2 from escherichia coli in complex with two atp molecules. Implications for substrate inhibition
(ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2008)
Crystallographic Structure of Phosphofructokinase-2 from Escherichia coli in Complex with Two ATP Molecules. Implications for Substrate Inhibition
(ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2008-08-22)
Phosphofructokinase-1 and -2 (Pfk-1 and Pfk-2, respectively) from
Escherichia coli belong to different homologous superfamilies. However, in
spite of the lack of a common ancestor, they share the ability to catalyze ...
Phenolic content, antioxidant activity and antiamylolytic activity of extracts obtained from bioprocessed pineapple and guava wastes
(Brazilian Journal of Chemical Engineering, 2012-03)
Evaluation of canonical siRNA and dicer substrate RNA for inhibition of hepatitis C virus genome replication: a comparative study
(Public Library Science, 2015-02-23)
Hepatitis C virus (HCV) frequently establishes persistent infections in the liver, leading to the development of chronic hepatitis and, potentially, to liver cirrhosis and hepatocellular carcinoma at later stages. The ...