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Evaluation of a protein deficient diet in rats through blood oxidative stress biomarkers
(2003-12-01)
Protein malnutrition leads to functional impairment in several organs, which is not fully restored with nutritional recovery. Little is known about the role of oxidative stress in the genesis of these alterations. This ...
Evaluation of a protein deficient diet in rats through blood oxidative stress biomarkers
(2003-12-01)
Protein malnutrition leads to functional impairment in several organs, which is not fully restored with nutritional recovery. Little is known about the role of oxidative stress in the genesis of these alterations. This ...
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
(2009)
Mutations in superoxide dismutase-1 (SOD1) cause familial amyotrophic lateral sclerosis (fALS). Recent evidence implicates adaptive responses to endoplasmic reticulum (ER) stress in the disease process via a pathway known ...
Intergenerational transmission of maternal care deficiency and offspring development delay induced by perinatal protein malnutrition
(Taylor & Francis, 2018-08)
Objectives: Early life represents a sensitive and critical period for an individual. Nutrition plays a crucial role in the maturation and functional development of the central nervous system. Inadequate nutrition before ...
Molecular chaperone Hsp90 as a target for oxidant-based anticancer therapies
(2011)
Hsp90 is a molecular chaperone involved in the stabilization of many oncoproteins that are required for the acquisition and maintenance of the so-called six major hallmarks of cancer cells. Various strategies have, therefore, ...
Deciphering the role of multiple thioredoxin fold proteins of leptospirillum sp. in oxidative stress tolerance
(MDPI, 2020)
Thioredoxin fold proteins (TFPs) form a family of diverse proteins involved in thiol/disulfide exchange in cells from all domains of life. Leptospirillum spp. are bioleaching bacteria naturally exposed to extreme conditions ...
Mild zinc deficiency in male and female rats: Early postnatal alterations in renal nitric oxide system and morphology
(Elsevier, 2013-03)
Objective
Fetal and postnatal zinc deficiencies induce an increase in arterial blood pressure and impair renal function in male adult rats. We therefore hypothesized that these renal alterations are present in early stages ...