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Human sperm chemotaxis: Both the oocyte and its surrounding cumulus cells secrete sperm chemoattractants
(Oxford University Press, 2005-03)
Background: Human sperm chemotaxis to pre-ovulatory follicular fluid is well established in vitro. However, it is not known whether the female's oocyte-cumulus complex secretes sperm chemoattractants subsequent to ovulation ...
Sperm Chemotaxis in Mammals
(Bentham Science Publishers, 2015)
Sperm cells evolved to acquire a sophisticated motility structure called a flagellum which gives spermatozoa a self-propelling force. Nonetheless, in internal fertilizing species such as mammals, the length and complexity ...
Lack of species-specificity in mammalian sperm chemotaxis
(Academic Press Inc Elsevier Science, 2003)
Sperm guidance in mammals - An unpaved road to the egg
(Nature Publishing Group, 2006-04-01)
Contrary to the prevalent view, there seems to be no competition in the mammalian female genital tract among large numbers of sperm cells that are racing towards the egg. Instead, small numbers of the ejaculated sperm cells ...
Sperm chemorepulsion, a supplementary mechanism to regulate fertilization
(Oxford University Press, 2017-08-01)
Study question. Are human spermatozoa able of chemorepulsive behavior? Summary answer. Capacitated human spermatozoa are able to be chemorepelled by synthetic Progesterone Receptor Ligands (sPRL, known as contraceptives) ...
Progesterone sperm chemoattraction may be modulated by its corticosteroid-binding globulin carrier protein
(Elsevier Science Inc, 2010-05-06)
Progesterone, the main steroidal component secreted by the cumulus cells that surround the egg, chemotactically guides human spermatozoa. The aim of this work was to evaluate whether the carrier protein corticosteroid-binding ...
A role for the chemokine receptor CCR6 in mammalian sperm motility and chemotaxis
(Wiley, 2014-01-01)
Although recent evidence indicates that several chemokines and defensins, well-known as inflammatory mediators, are expressed in the male and female reproductive tracts, the location and functional significance of chemokine ...
Mechanisms of the sperm guidance, an essential aid for meeting the oocyte
(AME Publishing, 2017-03)
In mammals, ejaculated spermatozoa must migrate into the female reproductive tract in order to reach and fertilize the oocyte (Figure 1). The number of spermatozoa that reach the oviductal isthmus (where they attach to ...
Progesterone at the picomolar range is a chemoattractant for mammalian spermatozoa
(Elsevier Science Inc, 2006-09)
By means of a videomicroscopy system and a computer image analysis, we performed chemotaxis assays to detect true chemotaxis in human spermatozoa, in parallel to immunohistochemistry detection of progesterone inside the ...
Chemotaxis of Capacitated Rabbit Spermatozoa to Follicular Fluid Revealed by a Novel Directionality-Based Assay
(Society for the Study of Reproduction, 2002-11-01)
Precontact communication between gametes is established by chemotaxis. Sperm chemotaxis toward factor(s) in follicular fluid (FF) has been demonstrated in humans and mice. In humans, the chemotactic responsiveness is ...