Prodrug design is a widely known molecular modification strategy that aims to optimize the physicochemical and pharmacological properties of drugs to improve their solubility and pharmacokinetic features and decrease their ...

Microemulsion electrokinetic capillary chromatography has been successfully applied to the separation and determination of water-soluble vitamins (thiamine hydrochloride, riboflavin, niacin, pyridoxine hydrochloride, folic ...

Methods for estimating solute solubilities in high temperature water both below and above its boiling point (under pressure) are needed for applications of this medium in processing applications such as sub-critical water ...

A static analytical equilibrium method was used to measure the binary and ternary solubilities of anthracene and p-terphenyl in subcritical water between 393 and 473 K and at 50 and 150 bar. Temperature was found to have ...

Water deficit is most frequent in forest physiognomies subjected to climate change. As a consequence, several tree species alter tissue water potential, gas exchange and production of carbon compounds to overcome damage ...

When the maximum complexing ability (MCA) of water-soluble complexants of unknown molecular weight is known, it is possible to calculate the stability constants of metal complexes where these complexants participate (2,4,5). ...

The assessment of the environmental fate and (eco)toxicological effects of pesticide compounds is of crucial importance. The present review is focused on Quantitative Structure-Property Relationships (QSPR) applications ...

The Extended Hildebrand Solubility Approach(EHSA) was applied in the presentwork to evaluate the solubility of theanalgesic drug acetaminophen (paracetamol)in polyethylene glycol 400 + watermixtures at 298.15 K. An ...