Now showing items 1-10 of 12307
The prodrug approach: A successful tool for improving drug solubility
Prodrug design is a widely known molecular modification strategy that aims to optimize the physicochemical and pharmacological properties of drugs to improve their solubility and pharmacokinetic features and decrease their ...
Rapid Determination of Water-Soluble and Fat-Soluble Vitamins in Commercial Formulations by MEEKC
(SPRINGER HEIDELBERG, 2010)
Microemulsion electrokinetic capillary chromatography has been successfully applied to the separation and determination of water-soluble vitamins (thiamine hydrochloride, riboflavin, niacin, pyridoxine hydrochloride, folic ...
Effect of 70-kDa and 148-kDa dextran hydrogels on praziquantel solubility
Praziquantel is an anthelmintic widely used in the treatment of schistosomiasis. Although a highly permeable drug, praziquantel is poorly soluble in water, limiting its bioavailability. Improving the solubility of poorly ...
Sobre clases de grupos finitos solubles
Solubility parameters, hydrophile-lipophile balance, and solubility in sucrose derivative surfactants obtained by GLC
(Asociación Química Argentina, 2002-11)
Specific retention volumes of different solvents were measured on coIumns containing two sucrose derivatives esters as stationary phase.Henry's constants were calculated and the solubility in the surfacnnts was obtaíned. ...
Solubility, porosity and fluid uptake of calcium silicate-based cements
(Univ Sao Paulo Fac Odontologia Bauru, 2018-01-01)
Objective: To evaluate the absorption/fluid uptake, solubility and porosity of White mineral trioxide aggregate (MTA) Angelus, Biodentine (BIO), and zinc oxide-eugenol (ZOE). Material and Methods: Solubility was evaluated ...
Preformulation studies of novel 5′-O-carbonates of lamivudine with biological activity: solubility and stability assays
(Taylor & Francis, 2013-07)
As a part of preformulation studies, the aim of this work was to examine the solubility and stability of a series of 50 -O-carbonates of lamivudine with proven antihuman immunodeficiency virus activity. Solubility studies ...
Whey proteins solubility as function of temperature and pH
(Elsevier Science BvAmsterdamHolanda, 2005)