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Assessment of the percutaneous penetration of cisplatin: The effect of monoolein and the drug skin penetration pathway
(ELSEVIER SCIENCE BV, 2009)
It was intended to examine the in vitro penetration of cisplatin (CIS) through porcine skin in the presence of different concentrations of monoolein (MO) as well as to verify the main barrier for CIS skin penetration. In ...
Evaluation of critical parameters for in vitro skin permeation and penetration studies using animal skin models
(2018-01-01)
In vitro skin permeation/penetration studies may be affected by many sources of variation. Herein, we aimed to investigate the major critical procedures of in vitro skin delivery studies. These experiments were performed ...
Penetration Profiles of a Class IV Therapeutic Laser and a Photobiomodulation Therapy Device in Equine Skin
(2020-02-01)
Photobiomodulation therapy (PBMT) effects depend on the energy settings and laser penetration. We investigated the penetration time profiles of two different light therapy devices, at the dark and light skin regions in ...
Storage conditions of skin affect tissue structure and in vitro percutaneus penetration
(Springer International Publishing, 2017)
For logistic and practical reasons, it is difficult to perform in vitro studies on percutaneous penetration on fresh human skin obtained directly from surgery. Skin samples are therefore often kept frozen until use. The ...
Skin Penetration of Epigallocatechin-3-Gallate and Quercetin from Green Tea and Ginkgo biloba Extracts Vehiculated in Cosmetic Formulations
(KARGER, 2009)
Green tea (Camellia sinensis) and Ginkgo biloba extracts in cosmetic formulations have been suggested to protect the skin against UV-induced damage and skin ageing. Thus, it is very important to assess the human skin ...
Liquid Crystal Nanodispersions Enable the Cutaneous Delivery of Photosensitizer for Topical PDT: Fluorescence Microscopy Study of Skin Penetration
(BENTHAM SCIENCE PUBL LTDSHARJAH, 2012)
Topical photodynamic therapy (PDT) has been applied to almost all types of nonmelanoma skin cancer and numerous superficial benign skin disorders. Strategies to improve the accumulation of photosensitizer in the skin have ...
Penetration of Quantum Dot Particles Through Human Skin
(AMER SCIENTIFIC PUBLISHERS, 2010)
The skin is a large and accessible area of the body, offering the possibility to be used as an alternative route for drug delivery. In the last few years strong progress has been made on the developing of nanoparticulate ...
The Use of Nanotechnology in Cosmetic Formulations: The Influence of Vehicle in the Vitamin A Skin Penetration
(BENTHAM SCIENCE PUBL LTDSHARJAH, 2013-08-02)
Despite the efficacy of topical retinoic acid, skin reactions have limited its acceptance by patients. Other retinoids, like Retinyl Palmitate (RP), are considerably less irritating, but they are also less effective. In ...
Enhanced skin penetration of P20 phosphopeptide using protein transduction domains
(ELSEVIER SCIENCE BV, 2008)
Protein transduction domains (PTDs) were recently demonstrated to increase the penetration of the model peptide P20 when the PTD and P20 were covalently attached. Here, we evaluated whether non-covalently linked PTDs were ...
Quercetin in w/o microemulsion: In vitro and in vivo skin penetration and efficacy against UVB-induced skin damages evaluated in vivo
(ELSEVIER SCIENCE BV, 2008)
The present study evaluated the potential of a w/o microemulsion as a topical carrier system for delivery of the antioxidant quercetin. Topical and transdermal delivery of quercetin were evaluated in vitro Using porcine ...