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Nanodrug Delivery Systems for Dermal and Transdermal Photosensitizer Drugs
(2017-03-29)
Skin is the largest organ in the human body and functions as a protective barrier. Molecules can penetrate the skin by three main routes: (1) intracellular (across the corneocytes), (2) intercellular lipids, and (3) ...
Recent advances and perspectives in liposomes for cutaneous drug delivery
(2018-02-01)
The cutaneous route is attractive for the delivery of drugs in the treatment of a wide variety of diseases. However the stratum corneum (SC) is an effective barrier that hampers skin penetration. Within this context, ...
Gene delivery to the skin – how far have we come?
Gene therapies are powerful tools to prevent, treat, and cure human diseases.
The application of gene therapies for skin diseases received little attention so
far, despite the easy accessibility of skin and the urgent ...
Nanotechnology-based drug delivery systems for treatment of hyperproliferative skin diseases - a review
(2013-04-12)
The chronic hyperproliferative diseases (CHD) include cancer, precancerous lesions and diseases of unknown etiology such as psoriasis. Various drugs have been used in the treatment of CHD, such as antiproliferative and ...
Nanotechnology-based drug delivery systems for treatment of hyperproliferative skin diseases - a review
(2013-04-12)
The chronic hyperproliferative diseases (CHD) include cancer, precancerous lesions and diseases of unknown etiology such as psoriasis. Various drugs have been used in the treatment of CHD, such as antiproliferative and ...
Skin delivery and in vitro biological evaluation of trans-Resveratrol-Loaded solid lipid nanoparticles for skin disorder therapies
(2016-01-01)
The aim of this study was to evaluate the skin delivery and in vitro biological activity of trans-resveratrol (RES)-loaded solid lipid nanoparticles (SLNs). The SLNs were composed of stearic acid, poloxamer 407, soy ...
Transdermal delivery of methotrexate: iontophoretic delivery from hydrogels and passive delivery from microemulsions
(ELSEVIER SCIENCE BV, 2001)
In vitro assays were performed to investigate the effectiveness of transdermal administration of methotrexate (MTX) by iontophoretic delivery from two types of hydrogel and passive delivery from two types of microemulsion. ...
Rheological, mechanical, and bioadhesive behavior of hydrogels to optimize skin delivery systems
(Informa Healthcare, 2013-11-01)
Background: Hydrogels are widely used for cutaneous formulations; thereby comparing the bioadhesive properties of polymers with a view to prolong the residence time of topical drugs on the skin would be very useful to ...