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Sister-chromatid exchanges in β-thalassaemic patients under conditions of in vivo and in vitro depletion of folic acid

Universidade Estadual Paulista (Unesp) (1992-07-02)

In order to investigate the effect of folate depletion, lymphocyte sister-chromatid exchange (SCE) rates were compared among homozygous β-thalassaemic patients with low folic acid levels, heterozygous β-thalassaemic patients ...

LYMPHOCYTE-PROLIFERATION AND SISTER CHROMATID EXCHANGE IN ALZHEIMERS-DISEASE

Melaragno, Maria Isabel [UNIFESP]; Smith, MDC; Kormann-Bortolotto, Maria Helena [UNIFESP]; Toniolo Neto, João [UNIFESP] (Karger, 1991-11-01)

Sister chromatid exchange (SCE) and lymphocyte proliferation were studied in peripheral lymphocyte cultures derived from 5 patients with Alzheimer disease (AD), 5 control elderly subjects and 5 young donors. These parameters ...

CYTOGENETIC ASPECTS of WERNERS-SYNDROME LYMPHOCYTE-CULTURES

Melaragno, M. I.; Pagni, D.; Smith, MDC (Elsevier B.V., 1995-03-01)

Lymphocyte cultures from five patients with Werner's syndrome (WS) and five healthy controls revealed significantly slower proliferation kinetics in four out of five patients. Higher frequencies of chromosome aberration ...

Sister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugs

Goloni-Bertollo, E. M. [UNESP]; Tajara, E. H. [UNESP]; Manzato, A. J. [UNESP]; Varella-Garcia, M. (Wiley-Blackwell, 2014)

Mechanism of anticlastogenicity of Agaricus blazei Murill mushroom organic extracts in wild type CHO (K-1) and repair deficient (xrs5) cells by chromosome aberration and sister chromatid exchange assays

Universidade Estadual de Londrina (UEL); Universidade Estadual Paulista (Unesp); Univ Luterana Brasil (Elsevier B.V., 2003-07-25)

Agaricus blazei Murill is a medicinal mushroom native to Brazil. The present work assessed the clastogenic and anticlastogenic potential of organic extracts (ethanol and chloroform/methanol) from the lineage AB97/11 in ...

SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS

Universidade Estadual Paulista (Unesp) (Soc Brasil Genetica, 1993-03-01)

Lymphocytes from beta thalassaemia heterozygote patients, with normal levels of plasma folic acid cultured for 72 h in a folate rich medium, were not found to contain increased rates of sister chromatid exchanges (SCE). A ...

Sister chromatid exchange and proliferation pattern in lymphocytes from newborns, elderly subjects and in premature aging syndromes

Melaragno, Maria Isabel [UNIFESP]; Smith, Marília de Arruda Cardoso [UNIFESP]; Melaragno, Maria Isabel [UNIFESP]; Smith, Marília de Arruda Cardoso [UNIFESP] (Elsevier B.V., 1990-05-15)

SISTER CHROMATID EXCHANGE FREQUENCY in A RETINOBLASTOMA MOSAIC PATIENT WITH DEL(13)

Melaragno, M. I.; Ribeiro, MCM; Smith, MDC; Andrade, JAD; Erwenne, C. M.; Melaragno, M. I.; Ribeiro, MCM; Smith, MDC; Andrade, JAD; Erwenne, C. M. (Elsevier B.V., 1988-06-01)

Ring chromosome instability evaluation in six patients with autosomal rings

Sodre, Claudete Palmer [UNIFESP]; Guilherme, Roberta dos Santos [UNIFESP]; Meloni, Vera de Freitas Ayres [UNIFESP]; Brunoni, Decio [UNIFESP]; Juliano, Yara; Andrade, Joyce Anderson Duffles [UNIFESP]; Belangero, Síntia Iole Nogueira [UNIFESP]; Christofolini, Denise Maria [UNIFESP]; Kulikowski, Leslie Domenici [UNIFESP]; Melaragno, Maria Isabel [UNIFESP] (Funpec-editora, 2010-01-01)

Ring chromosomes are often associated with abnormal phenotypes due to loss of genomic material and also because of ring instability at mitosis after sister chromatid exchange events. We investigated ring chromosome instability ...

EFFECT OF PRETREATMENT WITH VENOM OF APIS-MELLIFERA BEES ON THE YIELD OF GAMMA-RAY INDUCED CHROMOSOME-ABERRATIONS IN HUMAN BLOOD-LYMPHOCYTES

Universidade Estadual Paulista (Unesp) (Soc Brasil Genetica, 1993-09-01)

Venom of the honey bee Apis mellifera induced a protective effect against the induction of dicentric chromosomes by gamma radiation (2.0 Gy) in human peripheral blood lymphocytes which the cultures were treated with 0.00015 ...