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PHARMACOKINETIC STUDY OF RISPERIDONE: APPLICATION OF A HPLC METHOD WITH SOLID PHASE EXTRACTION
(Sociedad Chilena de Química, 2011)
Use of risperidone in children with epilepsy
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2007)
Optimization and in vivo toxicity evaluation of G4.5 PAMAM dendrimer-risperidone complexes
(Public Library of Science, 2014-02)
Risperidone is an approved antipsychotic drug belonging to the chemical class of benzisoxazole. This drug has low solubility in aqueous medium and poor bioavailability due to extensive first-pass metabolism and high protein ...
Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain
(ELSEVIER SCIENCE INCNEW YORK, 2012)
Second generation antipsychotics (SGAs) have been linked to metabolic and bone disorders in clinical studies, but the mechanisms of these side effects remain unclear. Additionally, no studies have examined whether SGAs ...
Long-acting injectable risperidone in partially adherent and nonadherent patients with schizophrenia
(DOVE MEDICAL PRESS LTD, 2011)
Background: Long-acting injectable antipsychotics may improve medication adherence, thereby improving overall treatment effectiveness. This study aimed to evaluate the effectiveness, safety, and tolerability of risperidone ...
Solid phase microextraction and LC-MS/MS for the determination of paliperidone after stereoselective fungal biotransformation of risperidone
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
The present work describes for the first time the use of SPME coupled to LC-MS/MS employing the polar organic mode in a stereoselective fungal biotransformation study to investigate the fungi ability to biotransform the ...
Time to rehospitalization in patients with schizophrenia discharged on first generation antipsychotics, non-clozapine second generation antipsychotics, or clozapine
(ELSEVIER IRELAND LTD, 2011)
Rehospitalization is an important outcome of drug effectiveness in schizophrenia. In this study, the hypothesis that clozapine and some second generation antipsychotics (SGA) were superior to first generation antipsychotics ...
G4.5 Pamam Dendrimer-Risperidone: Biodistribution and Behavioral Changes in In Vivo Model
(OMICS Publishing Group, 2013-12)
Dendritic polymers are considered as emerging and outstanding carriers as modern medicinal systems due to their derivatisable branched architecture and possibility to modify them in numerous ways. Here, G4.5 PAMAM dendrimers ...
Clinical outcomes of long-acting injectable risperidone in patients with schizophrenia: six-month follow-up from the Electronic Schizophrenia Treatment Adherence Registry in Latin America
(DOVE MEDICAL PRESS LTD, 2011)
Background: Risperidone long-acting injection (RLAI) has been shown to be efficacious, improve compliance, and increase long-term retention rate on therapy. The aim of this work was to determine the effect of RLAI on ...