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All-trans retinoic acid with daunorubicin or idarubicin for risk-adapted treatment of acute promyelocytic leukaemia: a matched-pair analysis of the PETHEMA LPA-2005 and IC-APL studies
(Springer, 2015)
Front-line treatment of acute promyelocytic leukaemia (APL) consists of all-trans retinoic acid (ATRA) and anthracycline-based chemotherapy. In this setting, a comparison of idarubicin and daunorubicin has never been carried ...
Physical exercise on the rat ventral prostate: Steroid hormone receptors, apoptosis and cell proliferation
(Wiley-blackwellHobokenEUA, 2012)
Intestinal protozoan infections in the immunocompromised host
(Wolters Kluwer Health, 2013)
Purpose of review: Intestinal protozoa are becoming increasingly recognized as significant pathogens in immunocompromised hosts. However, pathogenesis of infection is still poorly understood, diagnostic tests remain ...
Response to Initial Therapy Predicts Clinical Outcomes in Medullary Thyroid Cancer
(Mary Ann Liebert, Inc, 2015-02-01)
Background: Risk stratification in medullary thyroid cancer (MTC) has traditionally relied on standardized anatomic staging systems that, despite providing valuable prognostic information, do not adequately predict the ...
Adjuvant chemoradiation in resected gallbladder cancer: a prognostic index model for predicting overall survival
(Facultad de Medicina y Ciencia, 2019)
PurposePatients with gallbladder cancer (GBC) have a dismal prognosis. We investigated outcomes and risk factors for overall survival (OS) in patients treated with radical surgery and adjuvant chemoradiotherapy ...
Effectiveness of testosterone therapy in obese men with low testosterone levels, for losing weight, controlling obesity complications, and preventing cardiovascular events
(2018-04-01)
Background: The use of testosterone replacement therapy in obese men with low testosterone levels has been controversial. This review aims to analyze the effectiveness of testosterone therapy for weight loss and preventing ...
MET Signaling Pathways, Resistance Mechanisms, and Opportunities for Target Therapies
(2022)
The MET gene, known as MET proto-oncogene receptor tyrosine kinase, was first identified to induce tumor cell migration, invasion, and proliferation/survival through canonical RAS-CDC42-PAK-Rho kinase, RAS-MAPK, PI3K-AKT-mTOR, ...
Genetic and modifying factors that determine the risk of brain tumors
(2011-03-29)
Some modifying factors may determine the risk of brain tumors. Until now, it could not be attempted to identify people at risk and also to improve significantly disease progression. Current therapy consists of surgical ...
Genetic and modifying factors that determine the risk of brain tumors
(2011-03-29)
Some modifying factors may determine the risk of brain tumors. Until now, it could not be attempted to identify people at risk and also to improve significantly disease progression. Current therapy consists of surgical ...