Buscar
Mostrando ítems 1-10 de 50
Dicistronic MLV-retroviral vectors transduce neural precursors in vivoand co-express two genes in their differentiated neuronal progeny
(2005)
Abstract
Dicistronic MLV-based retroviral vectors, in which two IRESes independently initiate the translation of two proteins from a single RNA, have been shown to direct co-expression of proteins in several ...
Production of human factor VIII-FL in 293T cells using the bicistronic MGMT(P140K)-retroviral vector
(FUNPEC-EDITORARIBEIRAO PRETO, 2012)
Hemophilia A is the most common X-linked bleeding disorder; it is caused by deficiency of coagulation factor VIII (FVIII). Replacement therapy with rFVIII produced from human cell line is a major goal for treating hemophilia ...
Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector
(2010)
Abstract
Background
Gene therapy in the hematopoietic system remains promising, though certain aspects of vector design, such ...
Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector
(2010-01-22)
Abstract
Background
Gene therapy in the hematopoietic system remains promising, though certain aspects of vector design, such as transcriptional control elements, continue to ...
Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector
(2010-01-22)
Abstract
Background
Gene therapy in the hematopoietic system remains promising, though certain aspects of vector design, such as transcriptional control elements, continue to ...
Endostatin- and interleukin-2-expressing retroviral bicistronic vector for gene therapy of metastatic renal cell carcinoma
(WILEY-BLACKWELL, 2011)
Background Metastatic renal cell carcinoma (mRCC) is one of the most treatment-resistant malignancies. Despite all new therapeutic advances, almost all patients develop resistance to treatment and cure is rarely seen. In ...