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Chronic alcohol intake upregulates hepatic expression of carotenoid cleavage enzymes and PPAR in rats
(2010-10-01)
Excessive and chronic alcohol intake leads to a lower hepatic vitamin A status by interfering with vitamin A metabolism. Dietary provitamin A carotenoids can be converted into vitamin A mainly by carotenoid 15,15′-monooxygenase ...
The Visual Cycle in the Inner Retina of Chicken and the Involvement of Retinal G-Protein-Coupled Receptor (RGR)
(Springer, 2017-05-17)
The vertebrate retina contains typical photoreceptor (PR) cones and rods responsible for day/night vision, respectively, and intrinsically photosensitive retinal ganglion cells (ipRGCs) involved in the regulation of ...
The absence of transthyretin does not impair regulation of lipid and glucose metabolism
(Georg Thieme Verlag KgStuttgartAlemanha, 2007)
Low resolution structures of the retinoid X receptor DNA-binding and ligand-binding domains revealed by synchrotron x-ray solution scattering
(The American Society for Biochemistry and Molecular Biology, 2013)
Orphan nuclear receptor NGFI-B forms dimers with nonclassical interface
(2007-08-01)
The orphan receptor nerve growth factor-induced B (NGFI-B) is a member of the nuclear receptor's subfamily 4A (Nr4a). NGFI-B was shown to be capable of binding both as a monomer to an extended half-site containing a single ...
Expression and spectroscopic analysis of a mutant hepatitis B virus onco-protein HBx without cysteine residues
(Elsevier Science BvAmsterdamHolanda, 2005)
Computer-aided design of a novel ligand for retinoic acid receptor in cancer chemotherapy
(Wiley-Blackwell, 2005-05-05)
The isotypes of RAR and RXR are retinoic acid and retinoid X acid receptors, respectively, whose ligand-binding domain contains the ligand-dependent activation function, with distinct pharmacological targets for retinoids, ...