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Induction of protective effector immunity to prevent pathogenesis caused by the respiratory syncytial virus. Implications on therapy and vaccine design
(2014)
Human respiratory syncytial virus (hRSV) is the leading cause of respiratory illness in infants and young children around the globe. This pathogen, which was discovered in 1956, continues to cause a huge number of ...
New insights on the viral and host factors contributing to the airway pathogenesis caused by the respiratory syncytial virus
(2016)
The respiratory syncytial virus (RSV) is the most prevalent etiological agent of lower respiratory tract infections and the first cause of hospitalization in infants due to respiratory disease worldwide. However, efforts ...
Aberrant T cell immunity triggered by human Respiratory Syncytial Virus and human Metapneumovirus infection
(2017)
Human Respiratory syncytial virus (hRSV) and human metapneumovirus (hMPV) are the two major etiological viral agents of lower respiratory tract diseases, affecting mainly infants, young children and the elderly. Although ...
Respiratory Syncytial Virus: Pathology, therapeutic drugs and prophylaxis
(2014)
Human Respiratory Syncytial Virus (hRSV) is the leading cause of lower respiratory tract diseases, affecting particularly newborns and young children. This virus is able to modulate the immune response, generating a ...
Respiratory Syncytial Virus: Pathology, therapeutic drugs and prophylaxis
(2014)
Human Respiratory Syncytial Virus (hRSV) is the leading cause of lower respiratory tract diseases, affecting particularly newborns and young children. This virus is able to modulate the immune response, generating a ...
A safe and efficient BCG vectored vaccine to prevent the disease caused by the human Respiratory Syncytial Virus
(2017)
The human Respiratory Syncytial Virus (hRSV) causes lower respiratory tract infections including pneumonia and bronchiolitis. Such infections also cause a large number of hospitalizations and affects mainly newborns, young ...
Heme Oxygenase-1 Modulates Human Respiratory Syncytial Virus Replication and Lung Pathogenesis during Infection
(2017)
Human respiratory syncytial virus (hRSV) is the leading cause of severe lower respiratory tract infections in children. The development of novel prophylactic and therapeutic antiviral drugs against hRSV is imperative to ...
Respiratory syncytial virus detection in cells and clinical samples by using three new monoclonal antibodies
(2014)
Acute respiratory infections caused by the respiratory syncytial virus (RSV) are important health burdens that affect infants worldwide. RSV is also an important cause of morbidity and disease in adults, which causes ...
Contribution of Fc gamma receptors to human respiratory syncytial virus pathogenesis and the impairment of T-cell activation by dendritic cells
(2016)
Human respiratory syncytial virus (hRSV) is the leading cause of infant hospitalization related to respiratory disease. Infection with hRSV produces abundant infiltration of immune cells into the airways, which combined ...
Novel therapies and vaccines against the human respiratory syncytial virus
(2015)
Introduction: Human respiratory syncytial virus (hRSV) is the leading cause of acute lower respiratory tract infections worldwide in infants, as well as an important pathogen affecting the elderly and immunocompromised ...