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Participation of heat shock proteins in DNA repair mechanisms in cancer
(Nova Science Publishers, 2010)
Heat shock proteins (HSPs) are well known as molecular chaperones, playing important roles in cellular metabolism, escorting other proteins during aggregation, disaggregation, folding, and unfolding. They have been classified ...
Vascular repair by endothelial progenitor cells in an experimental model of metabolic syndrome
(Nova Science Publishers, 2012)
Feeding carbohydrate-enriched diets to normal rats has been shown to induce metabolic syndrome. Fructose-fed rats (FFR) have been used to assess the pathophysiological mechanisms involved in the development of this syndrome. ...
Damage and repair of the neuronal membrane: From neural development to axonal trauma and restoration
(Elsevier, 2019)
Integrity of the plasma membrane is essential for the maintenance of physiological conditions, metabolic activity and the shape of eukaryotic cells. In neurons, the plasma membrane surrounding the axon—the axolemma—fulfills ...
Vascular Repair and Remodeling: A Review
(IntechOpen, 2018)
Cardiovascular diseases (CVDs) such as ischemic heart disease (IHD), stroke, and peripheral artery disease (PAS) are the leading cause of mortality and morbidity around the world: about 30% of global deaths and 10% of ...
Concluding remarks
(Elsevier, Inc., 2017)
Mesenchymal Stromal Cells as Tumor Stromal Modulators provides the latest data on the heterogeneous cell population, reporting on topics such as immunomodulating, tissue repairing, differentiating, and their migratory and ...
Cell death in response to genotoxic stress and DNA damage:
(Cambridge University Press, 2011)
Cells are subjected to multiple types of stress throughout their life cycle, including starvation, infection, and physical and chemical agents. Stressors cause transient and permanent damage. Transient damage is reflected ...
Metabolism of Poly-ADP-ribose in Trypanosomatids
(Nova Science Publishers, Inc, 2010)
The poly-ADP-ribosylation reaction is a post-translational modification involved invarious cellular processes including DNA repair, DNA replication, gene expression,maintenance of genomic stability, cell death and cellular ...
Implications of heat shock proteins in carcinogenesis and cancer progression
(Springer, 2007)
Heat shock proteins (Hsp) participate in many events related to cancer as molecular chaperones, starting from the very beginning of carcinogenesis. Several etiological factors involve the Hsp family in their mechanisms of ...
Apicomplexan and histone variants: What's new?
(IntechOpen, 2019)
Plasmodium spp. and Toxoplasma gondii present a conserved nucleosome composition based on canonical H3 and variants, H4, canonical H2A and variants, and H2B. One-off, the phylum has also a variant H2B, named H2B.Z, which ...
Molecular mechanisms of cadmium toxicity in mammals
(Research Signpost, 2010)
Cadmium (Cd) is a toxic metal, targeting several organs, such as lungs, liver, kidneys, and testes, following acute intoxication. It produces nephrotoxicity, immunotoxicity, osteotoxicity, cardiotoxicity and tumors in human ...