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REMDESIVIR y COVID-19
(Centro de Información de Medicamentos (CIME), 2020-05)
Ante la gran cantidad de información circulante respecto a los medicamentos para el tratamiento de COVID-19 y considerando que es necesario ser objetivos respecto a la información fiable y científica disponible referente ...
Remdesivir and its antiviral activity against COVID-19: A systematic review
Background
To summarize the antiviral activities of remdesivir against SARS-CoV-2, the causative agent of COVID-19.
Methods
Available publications were systematically explored on some databases and gray literature was ...
Remdesivir: cuál es la evidencia para su utilización en el tratamiento de la infección por COVID-19Remdesivir: what is the evidence for its use in the treatment of COVID-19 infection?
(Ministerio de Salud de la Nación, 2020-10)
Si bien existe plausibilidad biológica para el uso de remdesivir en infecciones virales como las causadas por el nuevo coronavirus SARS-CoV-2, el verdadero lugar de este medicamento en el tratamiento de COVID-19 se conocerá ...
Modeling the Binding Mechanism of Remdesivir, Favilavir, and Ribavirin to SARS-CoV-2 RNA-Dependent RNA Polymerase
(American Chemical Society, 2021-01)
Recent efforts to repurpose drugs to combat COVID-19 have identified Remdesivir as a candidate. It acts on the RNA-dependent, RNA polymerase (RdRp) of the SARS-CoV-2 virus, a protein complex responsible for mediating ...
Remdesivir triphosphate blocks DNA synthesis and increases exonucleolysis by the replicative mitochondrial DNA polymerase, Pol γ
(2021-11-01)
The COVID-19 pandemic prompted the FDA to authorize a new nucleoside analogue, remdesivir, for emergency use in affected individuals. We examined the effects of its active metabolite, remdesivir triphosphate (RTP), on the ...
RACIM: ficha técnica de REMDESIVIR
(Red Argentina de Centros de Información de Medicamentos, 2020-07-01)
La Red Argentina de Centros de Información de Medicamentos (RACIM) elaboró fichas técnicas para profesionales de la salud sobre otros tratamientos que se están investigando en pacientes con COVID-19, en el marco de ensayos ...
Evolution of the Synthesis of Remdesivir: Classical Approaches and Most Recent Advances
(American Chemical Society, 2021-08)
The broad-spectrum antiviral Remdesivir, a monophosphate nucleoside analogue prodrug (ProTide), was repurposed. In May 2020, it received emergency approval by the FDA, being the first drug approved to fight the new coronavirus ...
Remdesivir use in the coronavirus disease 2019 Pandemic: A mini-review
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative
viral pathogen of coronavirus disease 2019 (COVID-19), appears to have various
clinical presentations and may result in severe respiratory ...
Use of remdesivir in patients with COVID-19: a systematic review and meta-analysis
(2022-01-01)
OBJECTIVE: Studies in the literature regarding the use of remdesivir to treat COVID-19 patients have shown conflicting results. This study sought to answer questions related to the use of remdesivir for the treatment of ...