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Modification of erythropoietin structure by N-homocysteinylation affects its antiapoptotic and proliferative functions
(Wiley Blackwell Publishing, Inc, 2018-10)
Many patients under therapy with recombinant human erythropoietin (rhuEPO) show resistance to the treatment, an effect likely associated with the accumulation of tissue factors, especially in renal and cardiovascular ...
Neuroprotective activity of a new erythropoietin formulation with increased penetration in the central nervous system
(Biomed central, 2011-11)
Apart from its hematopoietic effect, erythropoietin (EPO) is a molecule with high neuroprotective potential. However, its prolonged application may cause serious adverse effects due to the erythropoiesis stimulation. ...
Strategy for erythroid differentiation in ex vivo cultures: Lentiviral genetic modification of human hematopoietic stem cells with erythropoietin gene
(Soc Bioscience Bioengineering Japan, 2017-11)
If cultured in appropriate conditions, such as supplementing culture media with costly cytokines and growth factors, hematopoietic stem/progenitor cells (HSPCs) from different origins have shown to be an adequate source ...
Convulsive Stress Mimics Brain Hypoxia and Promotes the P-Glycoprotein (P-gp) and Erythropoietin Receptor Overexpression. Recombinant Human Erythropoietin Effect on P-gp Activity
(Frontiers Media S.A., 2019-07)
Erythropoietin (EPO) is not only a hormone that promotes erythropoiesis but also has a neuroprotective effect on neurons attributed to its known anti-apoptotic action. Previously, our group has demonstrated that recombinant-human ...
Eritropoyetina: más allá de la proliferación y maduración eritroide
(Universidad Militar Nueva Granada, 2010)
Eritropoyetina: más allá de la proliferación y maduración eritroide
(Universidad Militar Nueva Granada, 2010)
Effect of erythropoietin on mercury-induced nephrotoxicity: Role of membrane transporters
(SAGE Publications, 2021-03-10)
Mercury is a widespread pollutant. Mercuric ions uptake into tubular cells is supported by the Organic anion transporter 1 (Oat1) and 3 (Oat3) and its elimination into urine is through the Multidrug resistance-associated ...
Eritropoyetina como agente eritropoyético y no eritropoyético: consideraciones terapéuticasErythropoietic and non-erythropoietic functions of erythropoietin: therapeutic considerationsEritropoietina como agente eritropoiético e não eritropoiético: considerações terapêuticas
(Federación Bioquímica de la Provincia Buenos Aires, 2016-09)
La producción de glóbulos rojos es controlada continuamente para suplir ladesaparición de las células envejecidas y garantizar un aporte de oxígenoadecuado a todo el organismo. La citoquina pleitrópica eritropoyetina ...