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Fisiologia do eixo GH-sistema IGF
(Sociedade Brasileira de Endocrinologia e Metabologia, 2008)
O crescimento, principal característica da infância e da adolescência, apresenta padrão semelhante na maioria dos indivíduos. A herança genética e os componentes do eixo GH-IGF são os fatores que diretamente influenciam ...
Type 1 IGF Receptor Localization in Paediatric Gliomas: Significant Association with WHO Grading and Clinical Outcome
(Springer, 2018-06)
Nuclear localization of insulin-like growth factor receptor type 1 (IGF-1R) has been described as adverse prognostic factor in some cancers. We studied the expression and localization of IGF-1R in paediatric patients with ...
Fsh Stimulates Spermatogonial Proliferation and Differentiation in Zebrafish via Igf3
(Endocrine Soc, 2015-10-01)
Growth factors modulate germ line stem cell self-renewal and differentiation behavior. We investigate the effects of Igf3, a fish-specific member of the igf family. Fsh increased in a steroid-independent manner the number ...
Miostatina inhibe la vía de señalización IGF-1/PI3K/PLCγ/NFATc3 a través del receptor Activina tipo IB (ActRIB)
(Universidad Andrés Bello, 2017)
Miostatina, un miembro de la familia TGF-β, es una proteína expresada principalmente en el músculo esquelético que cumple un rol inhibidor en la proliferación y diferenciación de células musculares. Miostatina ejerce su ...
Woodhouse-Sakati syndrome: a case reportSíndrome de Woodhouse Sakati
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Humana, 2008)
Señalización celular en el folículo antral bovinoCellular Signaling in the Bovine Antral Follicles
(Universidad de los Llanos, Instituto de InvestigacionesBiogénesisVillavicencio, Colombia, 2023)
A Homozygous Mutation in the Highly Conserved Tyr60 of the Mature IGF1 Peptide Broadens the Spectrum of IGF1 Deficiency
(BioScientifica, 2019-09)
Background: IGF1 is a key factor in fetal and postnatal growth. To date, only three homozygous IGF1 gene defectsleading to complete or partial loss of IGF1 activity have been reported in three short patients born small ...