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Mitochondrial function and nitric oxide production in hippocampus and cerebral cortex of rats exposed to enriched environment
(Elsevier Science, 2010-03)
Male rats (21 days) were assigned to enriched environment (EE) or to standard environment (SE) for 1 year. Oxygen consumption and the sensitivity to calcium induced mitochondrial permeability transition (MPT), through ...
Mitochondrial function in rat cerebral cortex and hippocampus after short- and long-term hypobaric hypoxia
(Elsevier Science, 2015-02)
Taking into account the importance of aerobic metabolism in brain, the aim of the present work was to evaluate mitochondrial function in cerebral cortex and hippocampus in a model of sustained hypobaric hypoxia (5000 m ...
Prenatal exposure to the CB1 and CB2 cannabinoid receptor agonist WIN 55,212-2 alters migration of early-born glutamatergic neurons and GABAergic interneurons in the rat cerebral cortex
(Wiley, 2014-05)
The endocannabinoid system, composed of cannabinoid receptors, endocannabinoids, and synthesis and degradation enzymes, is present since early stages of brain development. During this period, the endocannabinoid system is ...
D4 dopamine and metabotropic glutamate receptors in cerebral cortex and striatum in rat brain
(Springer/Plenum Publishers, 2001-01)
The characterization of the functional interactions between the metabotropic glutamate receptors (mGluR) and the dopaminergic (DR) receptors in the corticostriatal projections may provide a possible interpretation of ...
Valproic acid has neuroprotective effect in an acute model of oxidative stress in ratsEl ácido valproico tiene efecto neuroprotector en un modelo de estrés oxidativo agudo en ratas
(Universidad Centroccidental Lisandro Alvarado, 2015)
Autoantibodies from schizophrenia patients induce cerebral cox-1/iNOS mRNA expression with NO/PGE2/MMP-3 production
(Cambridge University Press, 2010-04)
We demonstrated that circulating antibodies from schizophrenia patients, which interact with cerebral M1 muscarinic acetylcholine receptors (M1 mAChRs), trigger production of nitric oxide (NO), prostaglandin E2 (PGE2) and ...
Phosphatidic acid and diacylglycerol generation is regulated by insulin in cerebral cortex synaptosomes from adult and aged rats
(Veterinary and Human Toxicology, 2005-07)
Insulin receptor associated with the cerebral cortex (CC) has been shown to be involved in brain cognitive functions. Furthermore, deterioration of insulin signaling has been associated with age-related brain degenera tion. ...
Assessment transcallosal diaschisis in a model of focal cerebral ischemia in rats
(Facultad de Salud de la Universidad del ValleFacultad Ciencias de la SaludMedicinaDepartamento de Ciencias Básicas Médicas, 2016-04-01)
Objective: To evaluate transcallosal changes after a local ischemic injury in rats by using the monoclonal marker anti-NeuN (Mouse anti-neuronal nuclei). Methods: Twenty eight adult, male, Wistar rats were subjected to ...