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Electroretinography and immunohistochemistry of retina in rabbits treated with sildenafil citrate
(2015-01-01)
Sildenafil citrate is a type-5 phosphodiesterase inhibitor (PDE-5), able to inhibit type-6 phosphodiesterase (PDE-6) as well, providing clinical benefits and paraeffects, some of them potentially related to the retina. The ...
Neuroprotective effects of oral lamotrigine administration on rabbit retinas after pars plana vitrectomy and silicone oil injection
(LIPPINCOTT WILLIAMS & WILKINS, 2008)
Purpose: To investigate potential retinal neuroprotective effects of oral lamotrigine in rabbits after pars plana vitrectomy (PPV) and intravitreal silicone oil injection (SOI). Methods: Twelve New Zealand rabbits (weight, ...
Estudo da retina de coelhos após injeção intravítrea de bupivacaína
(Conselho Brasileiro de Oftalmologia, 2002-08-01)
Purpose: To evaluate morphologic alterations caused by intravitreous injection of bupivacaine, a long-term local anesthetic agent much used in ocular regional blockades, in the retina of albino rabbits. Methods: The drug ...
Rabbits' eye globe sonographic biometry
(Wiley-Blackwell, 2010-11-01)
ObjectiveTo measure intraocular structures in New Zealand White breed rabbits (Oryctolagus cuniculus Linnaeus, 1758) using A-mode and B-mode ultrasound with a 20 MHz transducer.ProceduresIn this study, the eyes of 15 rabbits ...
Reduced occurrence of programmed cell death and gliosis in the retinas of juvenile rabbits after shortterm treatment with intravitreous bevacizumab
(Faculdade de Medicina / USP, 2012)
OBJECTIVE: Bevacizumab has been widely used as a vascular endothelial growth factor antagonist in the treatment of retinal vasoproliferative disorders in adults and, more recently, in infants with retinopathy of prematurity. ...
Reduced occurrence of programmed cell death and gliosis in the retinas of juvenile rabbits after short-term treatment with intravitreous bevacizumab
(HOSPITAL CLINICAS, UNIV SAO PAULOSAO PAULO, 2012)
OBJECTIVE: Bevacizumab has been widely used as a vascular endothelial growth factor antagonist in the treatment of retinal vasoproliferative disorders in adults and, more recently, in infants with retinopathy of prematurity. ...
Evaluation of early abnormalities of the sensory retina in a hypercholesterolemia experimental model: an immunohistochemical study
(Conselho Brasileiro de Oftalmologia, 2009-12-01)
PURPOSE: The aim of this study is to demonstrate the early changes of the sensory retina induced by hypercholesterolemia in an experimental model. METHODS: New Zealand rabbits were divided into two groups: CG (Control ...
Pharmacokinetics of Melphalan after Intravitreal Injection in a Rabbit Model
(Mary Ann Liebert, 2016-05)
Purpose: Although widely used for vitreous seed control in retinoblastoma patients, currently there are no data on melphalan pharmacokinetics after intravitreal injections. Therefore, in this study, we characterized the ...
Vitreous pharmacokinetics and electroretinographic findings after intravitreal injection of acyclovir in rabbits
(HOSPITAL CLINICAS, UNIV SAO PAULOSAO PAULO, 2012)
OBJECTIVES: Acute retinal necrosis is a rapidly progressive and devastating viral retinitis caused by the herpesvirus family. Systemic acyclovir is the treatment of choice; however, the progression of retinal lesions ceases ...
Rabbits' eye globe sonographic biometry
(Wiley-Blackwell, 2010-11-01)
ObjectiveTo measure intraocular structures in New Zealand White breed rabbits (Oryctolagus cuniculus Linnaeus, 1758) using A-mode and B-mode ultrasound with a 20 MHz transducer.ProceduresIn this study, the eyes of 15 rabbits ...