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Crosstalk between Rac1-mediated actin regulation and ROS production
(Elsevier Inc., 2018)
© 2018 Elsevier Inc.The small RhoGTPase Rac1 is implicated in a variety of events related to actin cytoskeleton rearrangement. Remarkably, another event that is completely different from those related to actin regulation ...
Calcium & ROS: two orchestra directors for the requiem of death
(Elsevier, 2020)
Tumor necrosis factor alpha (TNF) triggers regulated necrosis of mycobacterium-infected macrophages through of mitochondrial reactive oxygen species (mitoROS) production in a RIPK1/3-dependent manner. To explain that, Roca ...
Oxidative stress in the local and systemic events of apical periodontitis
(Frontiers Media SA, 2017)
Oxidative stress is involved in the pathogenesis of a variety of inflammatory disorders. Apical periodontitis (AP) usually results in the formation of an osteolytic apical lesion (AL) caused by the immune response to ...
Dual and opposite roles of reactive oxygen species (ROS) in chagas disease: beneficial on the pathogen and harmful on the host
(Hindawi, 2020)
Chagas disease is a neglected tropical disease, which affects an estimate of 6-7 million people worldwide. Chagas disease is caused by Trypanosoma cruzi, which is a eukaryotic flagellate unicellular organism. At the primary ...
c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells
(BioMed Central Ltd., 2014)
© 2014 Tobar et al.; licensee BioMed Central Ltd. Background: Hard consistency, developed under the influence of tumor cell factors, is a characteristic feature of a breast tumor. Activation of resident fibroblasts leading ...
Comparative effects of superoxide anion and hydrogen peroxide on microsomal and cytosolic glutathione S-transferase activities of rat liver
(2010)
Glutathione S-transferases (GSTs) are isoenzymes occurring in the cytoplasm and as integral membrane proteins. In addition to their role in drug metabolism by conjugating electrophilic and lipophilic compounds with glutathione ...
TNF-α increases production of reactive oxygen species through Cdk5 activation in nociceptive neurons
(Frontiers Media, 2018)
The participation of reactive oxygen species (ROS) generated by NOX1 and NOX2/NADPH oxidase has been documented during inflammatory pain. However, the molecular mechanism involved in their activation is not fully understood. ...
TNF-alpha increases production of reactive oxygen species through Cdk5 activation in nociceptive neurons
(Frontiers Media SA, 2018)
The participation of reactive oxygen species (ROS) generated by NOX1 and NOX2/NADPH oxidase has been documented during inflammatory pain. However, the molecular mechanism involved in their activation is not fully understood. ...
ROS production via P2Y1-PKC-NOX2 is triggered by extracellular ATP after electrical stimulation of skeletal muscle cells
(Public Library of Science, 2015)
© 2015 Díaz-Vegas et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
Quercetin and related flavonoids conserve their antioxidant properties despite undergoing chemical or enzymatic oxidation
(Elsevier, 2017)
Oxidation of a phenolic group in quercetin is assumed to compromise its antioxidant properties. To
address this assumption, the ROS-scavenging, Folin-Ciocalteau- and Fe-reducing capacities of quercetin
and thirteen ...