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Towards a comprehensive picture of C-to-U RNA editing sites in angiosperm mitochondria
(Springer, 2018-06)
Key message: Our understanding of the dynamic and evolution of RNA editing in angiosperms is in part limited by the few editing sites identified to date. This study identified 10,217 editing sites from 17 diverse angiosperms. ...
Clinical Applications of RNA Editing Technology for the Early Detection of Cancer and Future Directions
(SAGE Publications, 2020-01)
Early detection of cancer has great clinical importance and potentially improves cure, survival rate and treatment outcome. RNA editing technology can be used as targeted and precise molecular scissors to cut and replace ...
RNA editing in plant mitochondria, cytoplasmic male sterility and plant breeding.
(Pontificia Universidad Católica de Valparaíso, 1998)
Agent-based model of genotype editing
(MIT Press, 2007-08-17)
Evolutionary algorithms rarely deal with ontogenetic, non-inherited alteration of genetic information because they are based on a direct genotype-phenotype mapping. In contrast, several processes have been discovered in ...
Guide RNA Repertoires in the Main Lineages of Trypanosoma cruzi: High Diversity and Variable Redundancy Among Strains
(Frontiers Media, 2021-05-31)
Trypanosoma cruzi, as other kinetoplastids, has a complex mechanism of editing of mitochondrial mRNAs that requires guide RNAs (gRNAs) coded in DNA minicircles in the kinetoplast. There are many variations on this mechanism ...
ADAR1 Transcriptome editing promotes breast cancer progression through the regulation of cell cycle and DNA damage response
(Elsevier B.V., 2020)
RNA editing has emerged as a novel mechanism in cancer progression. The double stranded RNA-specific adenosine deaminase (ADAR) modifies the expression of an important proportion of genes involved in cell cycle control, ...
ADAR1 Transcriptome editing promotes breast cancer progression through the regulation of cell cycle and DNA damage response
(Elsevier, 2020)
RNA editing has emerged as a novel mechanism in cancer progression. The double stranded RNA-specific adenosine deaminase (ADAR) modifies the expression of an important proportion of genes involved in cell cycle control, ...