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Oral squamous carcinoma cells secrete RANKL directly supporting osteolytic bone loss
(Elsevier B.V., 2013-02-01)
Objective: Local invasion of bone is a frequent complication of oral squamous cell carcinoma (OSCC). Development of these osteolytic lesions is mediated by osteoclasts. Receptor activation of NF-kappa B ligand (RANKL) ...
RANKL expression is differentially modulated by TLR2 and TLR4 signaling in fibroblasts and osteoblasts
(2014)
Resident, non-immune cells express various pattern-recognition receptors and produce inflammatory cytokines in response to microbial antigens, during the innate immune response. Alveolar bone resorption is the hallmark of ...
Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease
(2010-12-01)
Accumulated lines of evidence suggest that hyperimmune responses to periodontal bacteria result in the destruction of periodontal connective tissue and alveolar bone. The etiological roles of periodontal bacteria in the ...
Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease
(2010-12-01)
Accumulated lines of evidence suggest that hyperimmune responses to periodontal bacteria result in the destruction of periodontal connective tissue and alveolar bone. The etiological roles of periodontal bacteria in the ...
Role of the nuclear factor kappa Beta ligand (RANKL) in osteoarthritis and oseteoclastogenesis in thoroughbred horses. Use of anti-inflammatory drugs.Rol del ligando del factor nuclear kappa Beta (RANKL) en osteoartritis y osteoclastogénesis de equinos fina sangre de carrera. Uso de antiinflamatorios
(Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria, 2021)
Hypertension modifies OPG, RANK, and RANKL expression during the dental socket bone healing process in spontaneously hypertensive rats
(Springer, 2015-07-01)
Objective The aim of this study was to evaluate the dental socket bone healing process by histomorphometric and immunohistochemical analysis of osteoprotegerin (OPG), receptor activator of nuclear factor-kappa beta (RANK), ...
RANK/RANKL/OPG expression in rapid maxillary expansion
(2017-08-02)
The aim of this study was to evaluate osteoclastogenesis signaling in midpalatal suture after rapid maxillary expansion (RME) in rats. Thirty male Wistar rats were randomly assigned to two groups with 15 animals each: ...
Triiodothyronine (T3) does not induce rankl expression in rat ROS 17/2.8 Cells
(2008-01-01)
Osteoclastogenesis may be regulated via activation of the RANK/RANKL (receptor activator of nuclear factor-kappa B/ receptor activator of nuclear factor-kappa B ligand) system, which Is mediated by osteoblasts. However, ...
The increased expression of receptor activator of nuclear-κB ligand (RANKL) of multiple myeloma bone marrow stromal cells is inhibited by the bisphosphonate ibandronate
(2010)
The receptor activator of nuclear factor-kappaB ligand (RANKL) and interleukin-1beta are osteoclast activating factors which are abnormally expressed in bone marrow stromal cells and plasma cells of multiple myeloma patients. ...