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Effect of pulmonary hypertension in exercise tolerance in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis
(European Respiratory Soc Journals, 2020)
Chromosome 22q11 deletion in a patient with pulmonary atresia, intact ventricular septum, and confluent branch pulmonary arteries
(Cambridge University Press, 2018)
In this study, we report a patient with pulmonary atresia with intact ventricular septum (PA/IVS), confluent pulmonary arteries supplied by an arterial duct, and chromosome 22q11.2 microdeletion. The 22q11.2 deletion ...
2-Aminoethyldiphenylborinate modifies the pulmonary circulation in pulmonary hypertensive newborn lambs partially gestated at high altitude
(Amer Physiological Soc., 2016)
Calcium signaling through store-operated channels (SOC) is involved in hypoxic pulmonary hypertension. We determined whether a treatment with 2-aminoethyldiphenylborinate (2-APB), a compound with SOC blocker activity, ...
The role of nitric oxide signaling in pulmonary circulation of high- and low-altitude newborn sheep under basal and acute hypoxic conditions
(Academic Press Inc., 2019)
Nitric oxide (NO) is the main vasodilator agent that drives the rapid decrease of pulmonary vascular resistance for the respiratory onset during the fetal to neonatal transition. Nevertheless, the enhanced NO generation ...
Purinergic receptor stimulation induces calcium oscillations and smooth muscle contraction in small pulmonary veins
(Wiley, 2018-07)
The small pulmonary veins (SPVs) may play a role in the development of pulmonary hypertension and pulmonary oedema via active changes in SPV diameter, mediated by vascular smooth muscle cell (VSMC) contraction. However, ...
Mid-term follow-up of balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: An experience in Latin America
(Wiley, 2020)
Objectives To describe the characteristics of patients who undergo balloon pulmonary angioplasty (BPA) for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) and report the mid-term outcomes. Background BPA ...
Effects of Pulmonary Hypertension on Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease
(Elsevier, 2020)
Introduction: The impact of pulmonary hypertension (PH) on exercise tolerance in chronic obstructive pulmonary disease (COPD) has not been fully elucidated. It is necessary to characterize pulmonary hemodynamics in patients ...
Survival of patients with pulmonary arterial hypertension after the advent of specific pulmonary vasodilator therapies
(Soc. Médica Santiago, 2016)
Background: Pulmonary arterial hypertension (PAH) is a rare and progressive disease. Long-term survival remains poor despite of advances in specific vasodilator therapy. Aim: To describe the survival rate in a cohort of ...
Differences in health policies for drug availability in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension across Latin America
(USA, 2022-01-05)
Treatment for pulmonary arterial hypertension and chronic thromboembolicpulmonary hypertension in Latin America differs between countries, withregard to disease etiology, health insurance coverage, and drug availability. ...
Fetal and postnatal pulmonary circulation in the Alto Andino
(Elsevier, 2011)
Lowland mammals at high altitude constrict the pulmonary vessels, augmenting vascular resistance and
developing pulmonary arterial hypertension. In contrast, highland mammals, like the llama, do not
present pulmonary ...