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Mutación del gen BRAF en pacientes con cánceres de colon y recto con KRAS no mutado
(Sociedad Médica de Santiago, 2014)
Background: In colorectal cancer, BRAF and KRAS mutation are mutually
exclusive, but both are independent prognostic factors for the disease. Aim: To
determine the frequency of BRAF V600E mutation in colorectal cancer. ...
Mutación del gen BRAF en pacientes con cánceres de colon y recto con KRAS no mutado
(Sociedad Médica de Santiago, 2014)
Background: In colorectal cancer, BRAF and KRAS mutation are mutually
exclusive, but both are independent prognostic factors for the disease. Aim: To
determine the frequency of BRAF V600E mutation in colorectal cancer. ...
Sobre dinámica estructural y conservación de residuos en la superfamilia ras
(Universidad Nacional de Colombia, Facultad de Ciencias, Departamento de Biología, 2002)
SUPERFAMILIARASSe estima que la superfamilia Ras contiene 60 - 100 miembros que cumplen diferentesfunciones en el medio celular: transducción de señales (Ras), regulación del citoesque-leto (Rho), señalamiento vesicular ...
Targeting hodgkin and reed–sternberg cells with an inhibitor of heat-shock protein 90: Molecular pathways of response and potential mechanisms of resistance
(Molecular Diversity Preservation International, 2018-03)
Classical Hodgkin lymphoma (cHL) cells overexpress heat-shock protein 90 (HSP90), an important intracellular signaling hub regulating cell survival, which is emerging as a promising therapeutic target. Here, we report the ...