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Protein Carbonyl, But Not Malondialdehyde, Is Associated With ICU Mortality in Patients With Septic Shock
(2019-08-01)
Background: The objective of our study was to evaluate the association of serum malondialdehyde (MDA) and protein carbonyl concentration with intensive care unit (ICU) mortality in patients with septic shock. Methods: We ...
Protein carbonyl concentration as a biomarker for development and mortality in sepsis-induced acute kidney injury
(2018-01-25)
The objective of the present study was to evaluate protein carbonyl concentration as a predictor of AKI development in patients with septic shock and of renal replacement therapy (RRT) and mortality in patients with SAKI. ...
Serum thiamine concentration and oxidative stress as predictors of mortality in patients with septic shock
(Elsevier B.V., 2014-02-01)
Purpose: The purpose of the study is to determine the influence of serum thiamine, glutathione peroxidase (GPx) activity, and serum protein carbonyl concentrations in hospital mortality in patients with septic shock.Materials ...
Lipid damage is the best marker of oxidative injury during the cardiac remodeling process induced by tobacco smoke
(2018-11-16)
BACKGROUND: Oxidative stress is one potential mechanism that explain the direct effects of smoking on cardiac remodeling process. However, no study has compared different myocardial products of macromolecule oxidation after ...
Protein carbonylation and adipocyte mitochondrial function
(2012)
Carbonylation is the covalent, non-reversible modification of the side chains of cysteine, histidine, and lysine residues by lipid peroxidation end products such as 4-hydroxy- and 4-oxononenal. In adipose tissue the effects ...
HSP72 as a complementary protection against oxidative stress induced by exercise in the soleus muscle of rats
(Amer Physiological SocBethesdaEUA, 2000)
Yeast frataxin mutants display decreased superoxide dismutase activity crucial to promote protein oxidative damage
(Elsevier Science Inc, 2010-02-01)
Iron overload is involved in several pathological conditions, including Friedreich ataxia, a disease caused by decreased expression of the mitochondrial protein frataxin. In a previous study, we identified 14 proteins ...