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Gold Nanoparticles as Nucleation Centers for Amyloid Fibrillation
(Springer, 2018)
The aggregation of proteins into amyloid fbrils is related to more than 30 diseases, including the most common neurodegenerative conditions. Amyloid fbrillation is a nucleation-dependent polymerization reaction where ...
Amyloid Precursor Protein in Central and Peripheral Cholinergic Synaptopathies
(Nova Science Publishers, 2011-05)
Alzheimer´s disease is the most widespread form of dementia in the elderly. One of the characteristics of this disease is the profound functional deficit of the cholinergic system as a consequence of synaptic loss. Amyloid ...
Small Molecule Inhibitors of Lysozyme Amyloid Aggregation
(Springer, 2020)
Influence of Gold Nanoparticles on the Kinetics of α-Synuclein Aggregation
(American Chemical Society, 2013-11)
α-synuclein (AS) is a small (140 amino acids), abundant presynaptic protein, which lacks a unique secondary structure in aqueous solution. Amyloid aggregates of AS in dopaminergic neurons of the midbrain are the hallmark ...