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Oxidation and nitration of ribonuclease and lysozyme by peroxynitrite and myeloperoxidase
(ELSEVIER SCIENCE INC, 2009)
In spite of the many studies on protein modifications by reactive species, knowledge about the products resulting from the oxidation of protein-aromatic residues, including protein-derived radicals and their stable products, ...
Role of peroxynitrite in macrophage microbicidal mechanisms in vivo revealed by protein nitration and hydroxylation
(Pergamon-elsevier Science LtdOxfordInglaterra, 2001)
Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals
(Royal Society of Chemistry, 2016)
The oxidation of tryptophan (Trp) residues, mediated by peroxyl radicals (ROO.), follows a complex mechanism involving free radical intermediates, and short chain reactions. The reactivity of Trp towards ROO. should be ...
The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function
(Elsevier Inc., 2017)
© 2017 Elsevier Inc. FtsZ (filamenting temperature-sensitive mutant Z) is a key protein in bacteria cell division. The wild-type Escherichia coli FtsZ sequence (FtsZwt) contains three tyrosine (Tyr, Y) and sixteen methionine ...
Free radicals derived from γ-radiolysis of water and AAPH thermolysis mediate oxidative crosslinking of eGFP involving Tyr-Tyr and Tyr-Cys bonds : the fluorescence of the protein is conserved only towards peroxyl radicals
(2020-04)
The enhanced green fluorescent protein (eGFP) is one of the most employed variants of fluorescent proteins. Nonetheless little is known about the oxidative modifications that this protein can undergo in the cellular milieu. ...
Aging and calorie restriction modulate yeast redox state, oxidized protein removal, and the ubiquitin-proteasome system
(ELSEVIER SCIENCE INC, 2011)
The ubiquitin-proteasome system governs the half-life of most cellular proteins. Calorie restriction (CR) extends the maximum life span of a variety of species and prevents oxidized protein accumulation. We studied the ...
Causal role of oxidative stress in unfolded protein response development in the hyperthyroid state
(Elsevier, 2015)
L-3,3',5-Triiodothyronine (T-3) induced liver oxidative stress underlies significant protein oxidation, which may trigger the unfolded protein response (UPR). Administration of daily doses of 0.1 mg T-3 for three consecutive ...
Free radicals derived from γ-radiolysis of water and AAPH thermolysis mediate oxidative crosslinking of eGFP involving Tyr-Tyr and Tyr-Cys bonds: the fluorescence of the protein is conserved only towards peroxyl radicals
(Elsevier, 2020)
The enhanced green fluorescent protein (eGFP) is one of the most employed variants of fluorescent proteins.
Nonetheless little is known about the oxidative modifications that this protein can undergo in the cellular ...