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Subcellular distribution of prostaglandin-E2 and prostaglandin-F(2α) in atrial tissue from patients with mitral valve disease
(1998)
The distribution of prostaglandin-E2 (PGE2) and prostaglandin-F(2α) (PGF(2α)) was studied in subcellular fractions isolated from homogenates of human atrial fresh tissue by differential centrifugation. Right and left atrial ...
Subcellular localization of prostaglandin-E2 in rat heart tissue
(1991)
It has been reported that isolated rat heart myocytes and cardiac mesenchymal cells convert arachidonic acid mainly into three types of prostaglandins (PGs): PGE2, PGF2α, and PGI2 [1]. In addition, we have demonstrated ...
Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E-2 production in human gingival fibroblasts
(Wiley-Blackwell, 2015)
Background: Granulation tissue remodeling and myofibroblastic differentiation
are critically important events during wound healing. Tobacco smoking has a
detrimental effect in gingival tissue repair. However, studies ...
Protein kinase CK2 promotes cancer cell viability via up-regulation of cyclooxygenase-2 expression and enhanced prostaglandin E2 production
(2011)
Augmented expression of protein kinase CK2 is associated with hyperproliferation and resistance to apoptosis in cancer cells. Effects of CK2 are at least partially linked to signaling via the Wnt/β-catenin pathway, which ...
Effects of captopril on prostaglandin-thromboxane relation during myocardial ischemia induced by ventricular pacing EFECTOS DE CAPTOPRIL EN LA RELACION PROSTAGLANDINA/TROMBOXANO DURANTE LA ISQUEMIA INDUCIDA POR ESTIMULACION VENTRICULAR
(1994)
To evaluate the possible role of captopril during pacing induced ischaemia we studied 7 patients with stable coronary artery disease. Coronary sinus blood levels of thromboxane-B2 (TXB2), prostaglandin-F1 alpha (PGI2), ...
Gastroprotective activity of ent-beyerene derivatives in mice: Effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls
(Elsevier, 2015)
Seventeen compounds (2-18) synthetized from the diterpenoid ent-beyer-15-en-18-ol (1) isolated from aerial part of Baccharis tola were tested for their gastroprotective activity on the model of HCl/EtOH-induced gastric ...
Gastroprotective activity of synthetic coumarins: Role of endogenous prostaglandins, nitric oxide, non-protein sulfhydryls and vanilloid receptors
(Elsevier, 2016)
Natural or synthetic coumarins showed gastroprotective and antiulcer activity in animal models. In this study, we have synthetized twenty coumarins using classic methods to evaluate their gastroprotective effects on the ...
Endometrial expression of selected transcripts in postpartum of primiparous Holstein cows with clinical and subclinical endometritis
(Elsevier, 2015)
Postpartum endometritis compromises milk production and fertility in high-producing dairy cows. Infection of the endometrium induces an inflammatory response with secretion of cytokines that lead to polymorphonuclear cells ...
Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: A genome-wide microarray study
(2011)
Objectives. The role of neuroinflammation in schizophrenia has been an issue for long time. There are reports supporting the hypothesis of ongoing inflammation and others denying it. This may be partly ascribed to the ...
Abrogation of prostaglandin E-2/EP4 signaling impairs the development of rag1(+) lymphoid precursors in the thymus of zebrafish embryos
(2007)
PGE(2) is involved in a wide variety of physiological and pathological processes; however, deciphering its role in early Mammalian development has been difficult due to the maternal contribution of PGE(2). To overcome this ...