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STABILITY STUDY OF PRAVASTATIN UNDER HYDROLYTIC CONDITIONS ASSESSED BY HPLC
(Sociedad Chilena de Química, 2008)
Pravastatin protection from cold stress in myocardium of rats
(Japan Heart Journal, Second Dept of Internal Med, 2003-03-01)
The aim of this research was to evaluate the possible protective effect of pravastatin on ultrastructural alterations induced by cold stress in the myocardium of rats.Sixteen EPM-Wistar rats (Rattus norvegicus albinus) ...
Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats
(Elsevier Sci Ireland LtdClareIrlanda, 2001)
Combination effect naringin and pravastatin in lipid profile and glucose in obese rats
(Elsevier - Science Direct, 2022)
Structural, Spectroscopic (NMR, IR, and Raman), and DFT Investigation of the Self-Assembled Nanostructure of Pravastatin-LDH (Layered Double Hydroxides) Systems
(AMER CHEMICAL SOCWASHINGTON, 2012)
Layered double hydroxide (LDH) nanocontainers, suitable as carriers for anionic drugs, were intercalated with Pravastatin drug using magnesium-aluminum and zinc-aluminum in a M-II/Al molar ratio equal 2 and different ...
PyrGF and GSTLN peptides enhance pravastatin's inhibition of 3-hydroxy-3-methyl-glutaryl coenzyme
(2021-12-01)
Two newly designed peptides, Pyr-GF and GSTLN, enhance pravastatin inhibition of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMGCoAR). In silico experiments have demonstrated the interaction of these peptides with ...
EFFECTS OF SIMVASTATIN AND PRAVASTATIN ON ENDOTHELIUM-DEPENDENT RELAXATION IN HYPERCHOLESTEROLEMIC RABBITS
(Gustav Fischer Verlag JenaJenaAlemanha, 1994)
Placental nitric oxide formation and endothelium-dependent vasodilation underlie pravastatin effects against angiogenic imbalance, hypertension in pregnancy and intrauterine growth restriction
(2019-04-01)
Pre-eclampsia and hypertensive disorders of pregnancy are frequently associated with foeto-placental growth restriction, and that may be triggered by angiogenic imbalance and endothelial dysfunction. Impaired nitric oxide ...
Rapid reversal of endothelial dysfunction in hypercholesterolaemic rabbits treated with simvastatin and pravastatin
(Blackwell ScienceCarltonAustralia, 1997)
Effect of inhalation exposure to toluene on the activity of organic anion transporting polypeptide (Oatp) using pravastatin as a probe drug in rats
(2018-07-03)
1. Toluene, used as a pure substance or in solvent mixtures, is the cause of occupational exposures of large numbers of workers in the world. The organic anion transporting polypeptides (OATP: human; Oatp: rodents) are ...