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In vitro activity of combinations of zinc chelators with amphotericin B and posaconazole against six Mucorales species
(American Society for Microbiology, 2019-05)
Mucormycosis is an emerging disease with high mortality rates. Few antifungal drugs are active against Mucorales. Considering the low efficacy of monotherapy, combination-therapy strategies have been described. It is known ...
Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole
(Public Library of Science, 2021)
Farmacocinética de posaconazol en la profilaxis y tratamiento de la infección fúngica invasora en niños inmunocomprometidos en un hospital pediátrico
(Sociedad Chilena de Infectología, 2018)
Background: There is no consensus on the optimal dosage use of posaconazole (PSC) for invasive fungal infection (IFI) in pediatric patients and normally it is adjusted with drug levels (DLs) >= 0.7 mu g/ml and >= 1.25 mu ...
Effect of Posaconazole in an in vitro model of cardiac fibrosis induced by Trypanosoma cruzi
(Science Direct, 2020)
Pharmacokinetics of posaconazol in the prophylaxis and treatment of invasive fungal infection in immunocompromised children in a pediatric hospital Farmacocinética de posaconazol en la profilaxis y tratamiento de la infección fúngica invasora en niños inm
(Sociedad Chilena de Infectologia, 2018)
© 2018, Sociedad Chilena de Infectologia. All rights reserved.Background: There is no consensus on the optimal dosage use of posaconazole (PSC) for invasive fungal infection (IFI) in pediatric patients and normally it is ...
Benznidazole and Posaconazole in Eliminating Parasites in Asymptomatic T. Cruzi Carriers: The STOP-CHAGAS Trial
(Elsevier, 2017)
BACKGROUND Benznidazole is recommended for treatment of Chagas infection. Effects of combination therapy with benznidazole and posaconazole have not been tested in Trypanosoma cruzi carriers.
OBJECTIVES The purpose of ...
Riesgo de infección fúngica invasora usando profilaxis con posaconazol versus otros azoles en pacientes con leucemia mieloide aguda que reciben trasplante de progenitores hematopoyéticos en el Hospital Nacional Edgardo Rebagliati Martins en el periodo mayo 2017 a mayo 2022
(Universidad Peruana Cayetano HerediaPE, 2022)
Las infecciones fúngicas invasoras (IFI) son una de las principales causas de complicaciones infecciosas en pacientes oncohematológicos y con trasplante de células progenitoras hematopoyéticas (TCPH), generando el aumento ...
Posaconazole MIC Distributions for Aspergillus fumigatus Species Complex by Four Methods: Impact of cyp51A Mutations on Estimation of Epidemiological Cutoff Values
(American Society for Microbiology, 2018)
Estimating epidemiological cutoff endpoints (ECVs/ECOFFS) may be hindered by the overlap of MICs for mutant and nonmutant strains (strains harboring or not harboring mutations, respectively). Posaconazole MIC distributions ...