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Large-scale Production And Purification Of Recombinant Protein From An Insect Cell/baculovirus System In Erlenmeyer Flasks: Application To The Chicken Poly(adp-ribose) Polymerase Catalytic Domain.

Miranda, E A; de-Murcia, G; Ménissier-de-Murcia, J (1997)

Host Cell Poly(ADP-ribose) glycohydrolase Is Crucial for Trypanosoma cruzi Infection Cycle

Vilchez Larrea, Salomé Catalina; Schlesinger, Mariana; Kevorkian, María Laura; Flawia, Mirtha Maria; Alonso, Guillermo Daniel; Fernandez Villamil, Silvia Hebe (Public Library Science, 2013-06-12)

Trypanosoma cruzi, etiological agent of Chagas´ disease, has a complex life cycle which involves the invasion of mammalian host cells, differentiation and intracellular replication. Here we report the first insights into ...

An Improved Nonisotopic Test To Screen A Large Series Of New Inhibitor Molecules Of Poly(adp-ribose) Polymerase Activity For Therapeutic Applications

Decker P.; Miranda E.A.; De Murcia G.; Muller S. (, 1999)

Current Treatments and New Possible Complementary Therapies for Epithelial Ovarian Cancer

Garrido, Maritza; Fredes, Allison; Lobos-González, Lorena; Valenzuela, Manuel; Vera, Daniela; Romero, Carmen (2021)

: Epithelial ovarian cancer (EOC) is one of the deadliest gynaecological malignancies. The late diagnosis is frequent due to the absence of specific symptomatology and the molecular complexity of the disease, which includes ...

Trypanocidal properties, structure-activity relationship and computational studies of quinoxaline 1,4-di-N-oxide derivatives

Autor desconocido (Elsevier, 2011)

Pyrazole and propenone quinoxaline derivatives were tested against intracellular forms of Leishmania peruviana and Trypanosoma cruzi. Both series were tested for toxicity against proliferative and non-proliferative cells. ...

Triple negative breast cancer: generalities, situation in Costa Rica and new trends for its treatment.Cáncer de mama triple negativo: generalidades, situación en Costa Rica y nuevas tendencias para su tratamiento.

Salinas Meza,, Adriana; Serrano Arias, Bruno; Soto Quesada, Ana Gabriela; Valenciano Fernández, Sofía; Mora Román, Juan José (Universidad de Costa Rica, 2018)

Nad(+) Repletion Improves Muscle Function In Muscular Dystrophy And Counters Global Parylation

Ryu; Dongryeol; Zhang; Hongbo; Ropelle; Eduardo R.; Sorrentino; Vincenzo; Mazala; Davi A. G.; Mouchiroud; Laurent; Marshall; Philip L.; Campbell; Matthew D.; Ali; Amir Safi; Knowels; Gary M.; Bellemin; Stephanie; Iyer; Shama R.; Wang; Xu; Gariani; Karim; Sauve; Anthony A.; Canto; Carles; Conley; Kevin E.; Walter; Ludivine; Lovering; Richard M.; Chin; Eva R.; Jasmin; Bernard J.; Marcinek; David J.; Menzies; Keir J.; Auwerx; Johan (Amer Assoc Advancement ScienceWashington, 2016)