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Dissolution Enhancement and Characterization of Nimodipine Solid Dispersions with Poloxamer 407 or PEG 6000
(TAYLOR & FRANCIS INCPHILADELPHIA, 2012)
The solid dispersion approach is an alternative to increase drug solubility. Many carriers have been studied, but there is few information about poloxamer 407 (P407). Consequently, the objective of this study was to evaluate ...
Thermosensitive poloxamer-based injectables as controlled drug release platforms for veterinary use: development and in-vitro evaluation
(International Research Journals Publishing House, 2011-09)
The aim of this work was to explore the potential of combining two different poloxamers (P407 and P188) with κ-carrageenan and sodium chloride for their utilization in the design of thermosensitive injectable depot systems ...
The role of stabilizers and mechanical processes on physico-chemical and anti-inflammatory properties of methotrexate nanosuspensions
(2020-06-01)
The aim of this study was to investigate two different mechanical processes (Ultra-turrax® and Sonication) and two stabilizers (Methyl cellulose (MC) and Poloxamer 407 (P407)) on the physico-chemical and anti-inflammatory ...
Budesonide-hydroxypropyl-beta-cyclodextrin inclusion complex in binary poloxamer 407/403 system for ulcerative colitis treatment: A physico-chemical study from micelles to hydrogels
(Elsevier B.V., 2016-02-01)
Budesonide (BUD) is a glucocorticoid widely used for the treatment of ulcerative colitis. In this work, we propose the study of the system BUD-HP-beta-CD inclusion complex incorporated into PL 407 and PL407-PL403 ...
DESENVOLVIMENTO TECNOLÓGICO, CARACTERIZAÇÃO E AVALIAÇÃO IN VITRO DE DISPERSÕES SÓLIDAS CONTENDO ÁCIDO FERÚLICO
(UNIVERSIDADE ESTADUAL DE PONTA GROSSABRFarmacos, Medicamentos e Biociências Aplicadas à FarmáciaPrograma de Pós Graduação Ciências FarmacêuticasUEPG, 2017)
Influence of chitosan-tripolyphosphate nanoparticles on thermosensitive polymeric hydrogels: structural organization, drug release mechanisms and cytotoxicity
(Taylor & Francis As, 2019-04-04)
Chitosan-tripolyphosphate (CS-TPP) nanoparticles containing naproxen (NPX) were dispersed in poloxamer (PL) as unique (PL407) or binary (PL407-PL403) systems. Nanoparticles presented diameter of similar to 250 nm and zeta ...
Injectable thermosensitive gels based in Poloxamer as modified drug release systems for veterinary use
(Colegio Farmaceuticos Provincia de Buenos Aires, 2010-12)
The purpose of this work is to explore the potential of combining poloxamer 407 and carrageenan for its utilization in an injectable depot drug release system. Reverse thermal gelation of these formulations allow the local ...