Now showing items 1-10 of 228
Marked bleeding diathesis in patients with platelet dysfunction due to a novel mutation in RASGRP2, encoding CalDAG-GEFI (p.Gly305Asp)
(Taylor & Francis Ltd, 2018-01)
Congenital platelet function disorders are often the result of defects in critical signal transduction pathways required for platelet adhesion and clot formation. Mutations affecting RASGRP2, the gene encoding the Rap ...
Regulation of mitochondrial function as a promising target in platelet activation-related diseases
(Elsevier Inc., 2019)
© 2019 Elsevier Inc.Platelets are anucleated cell elements produced by fragmentation of the cytoplasm of megakaryocytes and have a unique metabolic phenotype compared with circulating leukocytes, exhibiting a high coupling ...
Establishment of the first platelet-donor registry in Argentina
(Società Italiana di Medicina Trasfusionale e Immunoematologia, 2020-07)
Background: Platelet transfusions are necessary to prevent and treat haemorrhages in thrombocytopenic patients or those with severe platelet dysfunction. In Latin American countries, including Argentina, blood supplies ...
Gene expression of adipose tissue, endothelial cells and platelets in subjects with metabolic syndrome (Review)
(SPANDIDOS PUBL LTD, POB 18179, ATHENS, 116 10, GREECE, 2012)
Inhibition of human platelet aggregation by eosinophils
(Pergamon-elsevier Science LtdOxfordInglaterra, 2013)
Pkc And Akt Modulate Cgmp/pkg Signaling Pathway On Platelet Aggregation In Experimental Sepsis
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2015)
Downregulation of TREM-like transcript (TLT)-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia
(Ferrata Storti Foundation, 2018-12)
Germline RUNX1 mutations lead to thrombocytopenia and platelet dysfunction in familialplatelet disorder with predisposition to acute myelogenous leukemia. Multiple aspects ofplatelet function are impaired in these patients, ...